134253-06-8

Upstream product

• 116163-18-9 1-(1,1-dimethylethyl)-1,4-dihydro-6-fluoro-7-chloro-4-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester 
• 134253-05-7 (1S,5S)-3-Benzyl-3,6-diaza-bicyclo[3.2.0]heptane 
• 780-15-4 1-benzyl-3-hydroxymethyl-4-hydroxypyrrolidine 
• 134253-02-4 Methanesulfonic acid (3S,4R)-4-aminomethyl-1-benzyl-pyrrolidin-3-yl ester 
• 134253-03-5 Methanesulfonic acid (3S,4R)-1-benzyl-4-[(2,2,2-trifluoro-acetylamino)-methyl]-pyrrolidin-3-yl ester 
• 134253-00-2 Methanesulfonic acid (3S,4S)-1-benzyl-4-methanesulfonyloxymethyl-pyrrolidin-3-yl ester 
• 134253-04-6 1-((1R,5S)-3-Benzyl-3,6-diaza-bicyclo[3.2.0]hept-6-yl)-2,2,2-trifluoro-ethanone 

Relevant academic research and scientific papers

Synthesis of a new bridged diamine 3,6-diazabicyclo [3.2.0] heptane: Applications to the synthesis of quinolone antibacterials

Diprotected 3,6-diazabicyclo [3.2.0] heptane has been prepared by an highly efficient process. Selective deprotection, followed by condensation with 7-halogenoquinolones led to the naphthyridones 10 and 13 and the quinolone 14.