134255-85-9Relevant academic research and scientific papers
An Investigation into the Unusual Formation of an Isocoumarin by Acetylation of 2,3,6-Trimethoxytoluene with (E)-2-Methylbut-2-enoic Acid and Trifluoroacetic Anhydride
Botha, Marc E.,Giles, Robin G. F.,Moorhoff, Cornelis M.,Engelhardt, Lutz M.,White, Allan H.,et al.
, p. 89 - 95 (2007/10/02)
Prolonged reaction of 2,3,6-trimethoxytoluene with an excess of premixed (E)-2-methylbut-2-enoic acid and trifluoroacetic anhydride in air affords 5,6,8-trimethoxy-3,4,7-trimethylisocoumarin 11 in 66percent yield as the sole product isolated, the structur
