134266-22-1

Upstream product

• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 141-97-9 ethyl acetoacetate 
• 57-13-6 urea 
• 121-33-5 vanillin 

Downstream Products

• 134266-36-7 Benzoic acid N'-[4-(3-bromo-4-hydroxy-5-methoxy-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carbonyl]-hydrazide 
• 134266-33-4 4-(3-Bromo-4-hydroxy-5-methoxy-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid hydrazide 
• 134266-35-6 4-(3-Bromo-4-hydroxy-5-methoxy-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid N'-(2,4-dinitro-phenyl)-hydrazide 
• 134266-34-5 4-(3-Bromo-4-hydroxy-5-methoxy-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid N'-phenyl-hydrazide 

Relevant academic research and scientific papers

Microwave assisted solid phase catalyst-free Biginelli synthesis of 3,4-dihydropyrimidin-2(1H)-one and 3,4-dihydropyrimidin-2(1H)-thione: A green approach, characterization and molecular crystal structures

Solid phase catalyst-free Biginelli synthesis of novel 5-carbethoxy-4-(3-bromo-4-hydroxy-5-methoxyphenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one (C15H17BrN2O5) and 5-carbethoxy-4-(3-bromo-4-hydroxy-5-methoxyphe

Nickel Chloride Hexahydrate Catalyzed Multicomponent Biginelli's Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones

An efficient protocol is reported for the one-pot three-component Bignelli synthesis of a series of 3,4-dihydropyrimidine-2(1H)-ones and thiones in good yields (66–90%) from the aldehydes (4-benzyloxybenzaldehyde, 5-bromovanilin, 4-formyl-1-cyclohexene, a