13427-80-0Relevant articles and documents
Surface modified EuxLa1-xF3 nanoparticles as luminescent biomarkers: Still plenty of room at the bottom
Khudoleeva, Vladislava Yu.,Utochnikova, Valentina V.,Kalyakina, Alena S.,Deygen, Irina M.,Shiryaev, Andrey A.,Marciniak, ?ukasz,Lebedev, Vasiliy A.,Roslyakov, Ilya V.,Garshev, Alexey V.,Lepnev, Leonid S.,Schepers, Ute,Br?se, Stefan,Kuzmina, Natalia P.
, p. 348 - 355 (2017)
Investigation of the formation and luminescent properties of surface modified bimetallic lanthanide fluorides and their use in bioimaging is described. We have shown that the solvent during the wet synthesis of EuF3 nanoparticles affects the na
GREEN, COPPER-CATALYZED DISPROPORTIONATION OF AROMATIC AND HETEROAROMATIC CARBOXYLATES TO DICARBOXYLATES
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Paragraph 0123-0125, (2020/06/08)
The present application relates to a process for preparation of a compound of Formula (I) and Formula (IV): wherein is as described herein; and wherein and R are as described herein.
An improved and practical synthesis of tranexamic acid
Li, Zhenhua,Fang, Li,Wang, Jian,Dong, Liuhong,Guo, Yanna,Xie, Yuanyuan
, p. 444 - 448 (2015/03/30)
Tranexamic acid 1, a synthetic antifibrinolytic drug with the treatment being considered highly cost-effective in many countries, has been included in the WHO list of essential medicines. In this paper, we designed the synthesis of 1 via a novel seven-step route from the readily available starting material dimethyl terephthalate, performing with 99.6% purity in 59.2% overall yield. During the process, we successfully developed a direct and efficient method for the preparation of key intermediate methyl 4-(acetamidomethyl)benzoate by one-pot hydrogenation and acylation in acetic anhydride using Ni/Al2O3 as a catalyst. More importantly, it should be a straightforward and practical way to circumvent the usage of toxic reagents (CrO3, Cl2), solvent (CCl4), and expensive catalyst (PtO2), etc., that plagued the previous methodologies.
