134295-17-3Relevant academic research and scientific papers
Pseudoesters and derivatives. XXX. Synthesis of 5-substituted furan-2(5H)-ones by the regiospecific reaction of anions of enaminofuranones with electrophiles
De Ancos, Begona,Farin, Francisco,Maestro, M. Carmen,Martin, M. Rosario,Vicioso, M. Mercedes
, p. 3171 - 3182 (2007/10/19)
Reactions of lithium enolates 2a,b derived from 5-methoxy(or 5-ethylthio)-4-(pyrrolidin-1-yl)- furan-2(5H)-ones (1a,b) with various electrophiles, such as alkylating agents, aldehydes, phenyl isocyanate, acyl chlorides, and trimethylsilyl chloride, occur regiospecifically to give the corresponding 5-substituted derivatives in synthetically useful yields.
