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1-(2-TRIFLUOROMETHYL-PHENYL)-BUTANE-1,3-DIONE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

134301-24-9

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134301-24-9 Usage

Type of compound

Diketone derivative

Backbone structure

Butane-1,3-dione

Side group

Trifluoromethyl-phenyl

Primary use

Chemical intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals

Potential applications

Organic synthesis and medicinal chemistry

Versatility

Industrial and research applications

Check Digit Verification of cas no

The CAS Registry Mumber 134301-24-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,3,0 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 134301-24:
(8*1)+(7*3)+(6*4)+(5*3)+(4*0)+(3*1)+(2*2)+(1*4)=79
79 % 10 = 9
So 134301-24-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H9F3O2/c1-7(15)6-10(16)8-4-2-3-5-9(8)11(12,13)14/h2-5H,6H2,1H3

134301-24-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[2-(trifluoromethyl)phenyl]butane-1,3-dione

1.2 Other means of identification

Product number -
Other names 1-(2-TRIFLUOROMETHYL-PHENYL)-BUTANE-1,3-DIONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:134301-24-9 SDS

134301-24-9Downstream Products

134301-24-9Relevant academic research and scientific papers

Triketoacid inhibitors of HIV-integrase: A new chemotype useful for probing the integrase pharmacophore

Walker, Michael A.,Johnson, Timothy,Ma, Zhuping,Banville, Jacques,Remillard, Roger,Kim, Oak,Zhang, Yunhui,Staab, Andrew,Wong, Henry,Torri, Albert,Samanta, Himadri,Lin, Zeyu,Deminie, Carol,Terry, Brian,Krystal, Mark,Meanwell, Nicholas

, p. 2920 - 2924 (2007/10/03)

Integrase is one of three enzymes expressed by HIV and represents a validated target for therapy. This study reports on the discovery of a new triketoacid-based chemotype that selectively inhibits the strand transfer reaction of HIV-integrase. SAR studies showed that the template binds to integrase in a manner similar to the diketoacid-based inhibitors. Moreover, comparison of the new chemotype to two different diketoacid templates led us to propose two aryl-binding domains in the inhibitor binding site. This information was used to design a new diketoacid template with improved activity against the enzyme.

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