134312-48-4Relevant academic research and scientific papers
Intramolecular Cyclopropanation-Ring Fragmentation Leading to Spirocyclic Ring Construction: A Stereoselective Synthesis of β-Chamigrene
Adams, Julian,Lepine-Frenette, Carole,Spero, Denice M.
, p. 4494 - 4498 (1991)
The transannular cylopropanation of a keto carbene generated by Rh2(OAc)4 catalysis on a bicyclic dihydropyran nucleus provided a key oxatricyclic ketone intermediate for the synthesis of the spirocyclic ring construction.Selective fragmentation of
Synthesis of racemic β-chamigrene, a spiro[5.5]undecane sequiterpene
Antonsen, Simen,Stenstrom, Yngve,Skattebol, Lars
, p. 20664 - 20670 (2015/03/18)
The present paper describes a total synthesis of racemic β-chamigrene (1), a sesquiterpene with a spiro[5.5]undecane carbon framework. Compared with previously reported β-chamigrene syntheses, we were able to reduce the total number of reaction steps, whi
