134332-56-2

Upstream product

• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 134330-85-1 3-benzodioxanylmethyl)-N-benzyl)>aminopropylchloride 
• 134330-76-0 (S)-4-Chloro-5-(2-hydroxymethyl-1-pyrrolidinyl)-3(2H)-pyridazinone 
• 134330-80-6 2-<3-Benzodioxanylmethyl)-N-benzyl>aminopropyl>-4-chloro-5-(2-hydroxymethyl-1-pyrrolidinyl)-3(2H)-pyridazinone 

Relevant academic research and scientific papers

Studies of Pyridazine Compounds. XXVI. The Synthesis of Pyridazinopyrrolooxazines and a Pyridazinopyrrolothiazine

The tricyclic oxazines 3 and 5 were obtained by ring closure of (2-hydroxymethyl-1-pyrrolidinyl)-3(2H)-pyridazinones 2d,e,g, respectively, prepared from 4,5-dichloro-3(2H)-pyridazinones with L-prolinol.The synthesis of the thiazine analogue 4a was achieved by treatment of 2d with thionyl chloride and the subsequent reaction with sodium sulfide.The structures of the compounds were supported by spectroscopic evidence.