134340-92-4Relevant academic research and scientific papers
Design, diversity-oriented synthesis and structure activity relationship studies of quinolinyl heterocycles as antimycobacterial agents
Rachakonda, Venkatesham,Alla, Manjula,Kotipalli, Sudha Sravanti,Ummani, Ramesh
, p. 536 - 547 (2013)
The current study reports design and diversity oriented synthesis of novel bis heterocycles with a common 2-methyl, C-4 unsubstituted quinoline moiety as the central key heterocycle. Employing reagent based skeletal diversity approach; a facile synthesis
Design and synthesis of new N′-substituted-2-methylquinoline-3-carbohydrazides with antioxidant and antimicrobial activity
Maddela, Srinubabu,Venugopal, Muralidharan,Maddela, Rambabu,Ajitha, Makula
, p. 930 - 935 (2015/08/18)
Ten new N′-substituted-2-methylquinoline-3-carbohydrazide scaffolds have been synthesized, characterized by their physical and spectral data (IR, 1H NMR, and MS) and screened for in vitro antimicrobial and antioxidant activities. Results clearl
Inhibitors of VEGF receptors-1 and -2 based on the 2-((pyridin-4-yl)ethyl) pyridine template
Kiselyov, Alexander S.,Semenova, Marina,Semenov, Victor V.,Milligan, Daniel
, p. 1913 - 1919 (2007/10/03)
We have developed a series of novel potent ((pyridin-4-yl)ethyl)pyridine derivatives active against kinases VEGFR-1 and -2. Both specific and dual ATP-competitive inhibitors of VEGFR-2 were identified. Kinase selectivity could be controlled by varying the
