13435-22-8

Basic information

• Product Name: 1-butyl-2-methyl-imidazole
• Synonyms: 1-butyl-2-methyl-imidazole;IMidazole,1-butyl-2-Methyl- (7CI,8CI);1H-Imidazole,1-butyl-2-methyl-;30198-05-9
• CAS NO: 13435-22-8
• Molecular Formula: C₈H₁₄N₂
• Molecular Weight: 138.21
• Mol File: 13435-22-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 244.796°C at 760 mmHg (Cal.) ref.
• Flash Point: 101.8°C
• Appearance: /
• Density: 0.944g/cm3 (Cal.) ref.
• Vapor Pressure: 0.0465mmHg at 25°C
• Refractive Index: 1.506
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-butyl-2-methyl-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-butyl-2-methyl-imidazole(13435-22-8)
• EPA Substance Registry System: 1-butyl-2-methyl-imidazole(13435-22-8)

Safety Data

• Hazardous Substances Data: 13435-22-8(Hazardous Substances Data)

Usage

General Description

1-butyl-2-methyl-imidazole is a chemical compound that belongs to the imidazole family. It is a colorless liquid with a mild odor and is commonly used as a solvent, particularly in the extraction of various metals and as a catalyst in chemical reactions. 1-butyl-2-methyl-imidazole has also been found to be an effective corrosion inhibitor and has potential applications in the pharmaceutical and agrochemical industries. Its unique properties make it a versatile and valuable chemical in various industrial processes and research applications. However, it is important to handle this chemical with care and follow proper safety protocols due to its potential hazards.

InChI:InChI=1/C8H14N2/c1-3-4-6-10-7-5-9-8(10)2/h5,7H,3-4,6H2,1-2H3

Upstream product

• 693-98-1 2-methylimidazole 
• 542-52-9 Dibutyl carbonate 
• 1052104-58-1 2-methyl-1-[4-(phenylselanyl)butyl]-1H-imidazole 
• 109-65-9 1-bromo-butane 

Downstream Products

• 40229-82-1 1-butyl-2-methylimidazolium picrate 

Relevant articles and documents

Identification and characterization of a potent antibacterial agent, NH125 against drug-resistant bacteria

New imidazole compounds were synthesized to develop a novel and effective antibacterial agent (1-benzyl-3-cetyl-2-methylimidazolium iodide, NH125). In vitro experiments demonstrated that NH125 effectively inhibited a number of different histidine protein

Method for alkylating N1-position of imidazole compound

The present invention relates to a method for alkylating an N1-position of an imidazole compound and belongs to the technical field of organic synthesis. The method comprises the following steps: mixing an imidazole compound and carbonic ester with a molar ratio of 1:(1-2), conducting a heating reaction under a temperature of 80-140 DEG C under presence of aromatic hydrocarbons or a dipolar aprotic solvent and a strongly basic organic tertiary amine catalyst, and after reaction, directly conducting vacuum distillation or layering, and conducting vacuum distillation to obtain a N1 alkylated imidazole compound. The raw materials used in the method are non-toxic or low-toxic, the process is simple, reaction conditions are mild, and yield is high; and by-products in the reaction process are extremely few, environmental pollution is extremely small, and the preparation method is green and environmentally-friendly.

Regioselective C-H alkenylation of imidazoles and its application to the synthesis of unsymmetrically substituted benzimidazoles

A palladium-catalyzed C-H alkenylation of imidazoles has been developed. High C5 selectivity was achieved for C2-unsubstituted and C2-substituted imidazoles using oxygen and copper(ii) acetate, respectively, as oxidants. The obtained products were applied