13437-77-9

Basic information

• Product Name: 1-phenyl-5-(prop-2-enyloxy)-tetrazole
• Synonyms: 1-phenyl-5-(prop-2-enyloxy)-tetrazole
• CAS NO: 13437-77-9
• Molecular Weight: 202.216
• Mol File: 13437-77-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-phenyl-5-(prop-2-enyloxy)-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-5-(prop-2-enyloxy)-tetrazole(13437-77-9)
• EPA Substance Registry System: 1-phenyl-5-(prop-2-enyloxy)-tetrazole(13437-77-9)

Safety Data

• Hazardous Substances Data: 13437-77-9(Hazardous Substances Data)

Upstream product

• 14210-25-4 5-Chloro-1-phenyltetrazole 
• 107-18-6 allyl alcohol 

Downstream Products

• 1018667-83-8 N-phenyl-6H-1,3-oxazin-2-amine 
• 621-84-1 O-benzyl carbamate 
• 5834-97-9 1-allylidene-2-phenylhydrazine 
• 103-71-9 phenyl isocyanate 
• 62-53-3 aniline 
• 866639-44-3 3,4-dihydro-3-phenylpyrimidin-2(1H)-one 
• 13444-10-5 1,4-Dihydro-1-phenyl-4-(2-propenyl)-5H-tetrazol-5-on 
• 5097-82-5 5-phenyl-1H-tetrazolone 

Relevant articles and documents

Metal-assisted reactions. Part 25. Heterogeneous and homogeneous catalytic transfer hydrogenolysis of allyloxytetrazoles to yield alkenes or alkanes

Transfer hydrogenolysis of 5-allyloxy-1-phenyltetrazoles using either a heterogeneous or a homogeneous palladium catalyst and a hydrogen donor leads to cleavage of the allyloxy C-O bond to yield an alkane or an alkene and 1-phenyltetrazolone, depending on the catalyst used.

Mechanistic investigations into the photochemistry of 4-allyl-tetrazolones in solution: A new approach to the synthesis of 3,4-dihydro-pyrimidinones

Photolysis (λ = 254 nm) of 4-allyl-tetrazolones 2a-c was carried out in methanol, 1 -propanol, 1-hexanol, acetonitrile, and cyclohexane. The sole primary photochemical process identified was molecular nitrogen elimination, with formation of pyrimidinones 6a-c. Following the primary photocleavage, secondary reactions were observed in acetonitrile and cyclohexane, leading to phenyl-isocyanate (7), aniline (9), and 1-phenylprop-1-enyl-isocyanate (10a). In alcoholic solutions, the primary products, 6a-c, remained photostable even under extended irradiation, making possible the isolation of 3,4-dihydro-pyrimidinones as stable compounds in very high yields. The observed photostability of pyrimidinones 6a-c in alcohols is ascribed to the excited state quenching via reversible proton transfer, facilitated by the solvent cage stabilization due to formation of hydrogen bonds. The viscosity of alcohols is directly related to the cage effects observed. The photocleavage of 4-allyl-tetrazolones leads probably to a caged triplet radical pair. This hypothesis is confirmed by the solvent viscosity effect on the photolysis quantum yields. Additionally, dissolved molecular oxygen sensitizes the formation of pyrimidinones, as should be expected for a triplet intermediate that can only form the product molecule after T-S conversion, which is accelerated by oxygen.

A kinetic investigation of the thermal rearrangement of allyloxytetrazoles to N-allyltetrazolones

The mechanism of the thermal rearrangement of 1-aryl-5-allyloxytetrazoles 1 to give 1-aryl-4-allyltetrazolones 2 in very high yield has been investigated through kinetic studies in one polar and one less polar solvent. The results suggest mainly a concerted [3,3] sigmatropic process, in which a partially positively charged allyl group migrates from oxygen to nitrogen, similar to the polar transition state found in the Claisen rearrangement.