13438-29-4

Upstream product

• 499-49-0 5-methylisophthalic aicd 

Downstream Products

• 1080498-57-2 C₂₁H₂₈O₄ 
• 17649-58-0 5-Methylisophthalsaeure-dimethylester 
• 42268-88-2 1,3-dimethyl 5-(bromomethyl)benzene-1,3-dicarboxylate 
• 422550-81-0 N,N'-dimethoxy-N,N',5-trimethylisophthalamide 
• 39718-07-5 5-methylbenzene-1,3-dicarbonitrile 
• 87533-36-6 C₁₃H₂₀N₈*2ClH 
• 87533-52-6 1,3-diacetyl-5-methylbenzene 
• 90868-23-8 5-methyl-isophthalic acid diamide 

Relevant academic research and scientific papers

COMPOUND, POLYMER, PATTERN FORMING MATERIAL, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE

A pattern forming material is configured to use for forming an organic film on a film to be processed, patterning the organic film, and then forming a composite film by infiltrating a metallic compound into the patterned organic film. The pattern forming material contains a polymer including a monomer unit represented by a general formula (3) described below, where R21 is H or CH3, each R22 is a hydrocarbon group of C2-14 where α carbon is primary carbon, secondary carbon or tertiary carbon, Q is a single bond or a hydrocarbon group of C1-20 carbon atoms which may include an oxygen atom, a nitrogen atom, or a sulfur atom between carbon-carbon atoms of or at a bond terminal, and a halogen atom may be substituted for the hydrogen atom.

Diphosphametacyclophanes: Structural and electronic influences of substituent variation within a family of bis(diketophosphanyl) macrocycles

The condensation of MeP(SiMe3)2 with a series of 5-substituted isophthaloyl chlorides (5-R′C6H3-2,6-{C(O)Cl}2) affords the diphosphametacyclophanes m-{-C(O)-C6H3-5-R′-(C(O)PMe)}2 (R′ = I, Me, tBu, Ph, and p-NCC6H4); the analogues m-{-C(O)-C5H3N-(C(O)PMe)}2 and m-{-C(O)-C6H4-(C(O)PPh)}2 are similarly obtained in preference to higher oligomers, in contrast to precedent reports. The cyclophanes all adopt butterfly-like conformations in the solid state with the P-organyl substituents adopting mutually exo arrangements. Structural and computational data suggest the nature of the 5-R substituent is key in directing the inter-ring angle and the extent of LUMO stabilization about the diketophophanyl scaffold. The latter is substantiated by UV/vis spectroscopy and cyclic voltammetry, which demonstrate these cyclophanes to be appreciably comparable to the diketophosphanyl systems commonly explored in the context of organic electronic materials; intriguingly, the distinct dikeophosphanyl moieties within the macrocycles appear effectively “insulated” by the macrocycle geometry, rather than acting as a through-conjugate.

Identification and SAR Evaluation of Hemozoin-Inhibiting Benzamides Active against Plasmodium falciparum

Quinoline antimalarials target hemozoin formation causing a cytotoxic accumulation of ferriprotoporphyrin IX (Fe(III)PPIX). Well-developed SAR models exist for β-hematin inhibition, parasite activity, and cellular mechanisms for this compound class, but no comparably detailed investigations exist for other hemozoin inhibiting chemotypes. Here, benzamide analogues based on previous HTS hits have been purchased or synthesized. Only derivatives containing an electron deficient aromatic ring and capable of adopting flat conformations, optimal for π-π interactions with Fe(III)PPIX, inhibited β-hematin formation. The two most potent analogues showed nanomolar parasite activity, with little CQ cross-resistance, low cytotoxicity, and high in vitro microsomal stability. Selected analogues inhibited hemozoin formation in Plasmodium falciparum causing high levels of free heme. In contrast to quinolines, introduction of amine side chains did not lead to benzamide accumulation in the parasite. These data reveal complex relationships between heme binding, free heme levels, cellular accumulation, and in vitro activity of potential novel antimalarials.

Discrimination between alkyl and aryl substituents of chiral monoamines by m-phthalic diamide-linked zinc bisporphyrinates

m-Phthalic diamide-linked zinc bisporphyrinates have been developed as chirality probes for monoamines. They are capable of determining the absolute configuration of monoamines and distinguishing between alkyl and aryl substituents of chiral monoamines. Our studies suggest that steric interactions play critical roles in the molecular recognition process.

5-Substituted isophthalate-based organic electrochromic materials

A new series of isophthalate-based electrochromic materials were prepared. The functional groups at the 5-position of isophthalate have a significant influence on the observed color. In particular, an electrochemically active nitro group induced a multi-color display, indicating that further electrochromic properties could be manipulated using more diverse 5-substituted isophthalate derivatives. The Royal Society of Chemistry 2008.

4-substituted-phenyl(bisoxazoline)-rhodium complexes: Efficiency in the catalytic asymmetric reductive aldol reaction

Electronic effects of the substituents on the phenyl ring of the phenyl(bisoxazoline) ligand skeleton of rhodium catalysts was examined in the asymmetric reductive aldol reactions of acrylates and aldehydes. The electron-withdrawing NO2 group o

Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors

Certain aza- and polyaza-naphthalenyl ketones including certain quinolinyl and naphthyridinyl ketones are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment or the delay in the onset of AIDS, as compounds or pharmaceutically acceptable salts, or as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating or delaying the onset of AIDS and methods of preventing or treating infection by HIV are also described.