13440-76-1

Upstream product

• 32264-57-6 4,4,6,6-tetramethylcyclohex-2-en-1-one 
• 1073-13-8 4,4-dimethylcyclohexenone 
• 74-88-4 methyl iodide 
• 13395-71-6 2,4,4-trimethyl-2-cyclohexenone 
• 21592-93-8 4,4,6,6-Tetramethyl-cyclohexen-⁽²⁾-ol-⁽¹⁾ 

Downstream Products

• 1207109-99-6 6-hydroxymethylene-2,2,4,4-tetramethylcyclohexanone 
• 1207110-52-8 3,3,5,5-tetramethyl-2-oxocyclohexanecarbonitrile 
• 1207110-53-9 3,3,5,5-tetramethyl-2-oxocyclohex-1-enecarbonitrile 
• 427898-76-8 4,4,6,6-tetramethyl-2-(trifluoroacetyl)cyclohex-2-enone 
• 427898-75-7 2-acetyl-4,4,6,6-tetramethylcyclohex-2-enone 

Relevant academic research and scientific papers

Chromene compound

PROBLEM TO BE SOLVED: To provide a chromene compound having little discoloration in a non-irradiation state.SOLUTION: This chromene compound is represented by general formula (1) {in the formula, Ris an alkyl group; Rand Rare each independently a hydrogen atom, an alkyl group or an alkoxy group; Rand Rare each independently a hydrogen atom or the like; Rand Rare each independently a hydroxy group or the like; Rand Rare each independently an aryl group or the like; Z is a divalent group selected from an alkylene group, a cycloalkylene group or an arylene group; a is an integer of 0-2; and b is an integer of 0-4}.

Synthesis, chemical reactivity as michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents(1)

Novel monocyclic cyanoenones examined to date display unique features regarding chemical reactivity as Michael acceptors and biological potency. Remarkably, in some biological assays, the simple structure is more potent than pentacyclic triterpenoids (e.g

MONOCYCLIC CYANOENONES AND METHODS OF USE THEREOF

The present invention features monocyclic cyanoenone compositions and methods for using the same in the treatment of diseases such as cancer, inflammatory diseases and neurodegenerative diseases.