1344144-91-7

Upstream product

• 459-04-1 4-Fluorophenylacetyl chloride 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 159707-16-1 (4S)-benzyl-3-[2'-(4-fluorophenyl)acetyl]-2-oxazolidinone 
• 74-88-4 methyl iodide 

Downstream Products

• 1344144-92-8 (S)-2-(2-(4-fluorophenyl)propyl)isoindoline-1,3-dione 
• 1344144-93-9 (S)-2-(4-fluorophenyl)propan-1-amine 
• 1409946-85-5 3-[(5-{[(2S)-2-(4-Fluorophenyl)propyl]amino}-1,2,4-thiadiazol-3-yl)methyl]phenol 
• 1409946-82-2 [(2S)-2-(4-fluorophenyl)propyl]{3-[(3-methoxyphenyl)methyl](1,2,4-thiadiazol-5-yl)}amine 
• 191725-90-3 (S)-4-fluoro-α-methylphenylacetic acid 

Relevant academic research and scientific papers

MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS

The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof wherein Z, R1, R2, R3, R4, R5 and R6 are as defined in the specification, a process for

INDANE DERIVATIVES AS MGLUR7 MODULATORS

The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4a and R4b are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds of formula (I) are mGluR7 modulators.

Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use

Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R2, R4, R5, R6, R7, R8, R9, X, Z1, Z2, Z3, Z4 and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.

CERTAIN HETEROCYCLES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE

Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, X, Z1, Z2, Z3, Z4 and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.