1344156-69-9Relevant academic research and scientific papers
Cysteine fluorescent probe and preparation method and application thereof
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Paragraph 0033-0034, (2021/09/08)
The invention discloses a cysteine fluorescent probe and a preparation method and application thereof. The cysteine fluorescent probe comprises quinolinium ions serving as a framework, trimethylsilyl bonded with the quinolinium ion skeleton structure through a carbon-silicon single bond, and a p-phenyl acrylate group and counter ions which are connected with the quinolinium ion skeleton structure through a carbon-carbon single bond. The fluorescence intensity of the cysteine fluorescent probe is almost completely quenched when cysteine is added, the fluorescence intensity of the cysteine fluorescent probe and the concentration of cysteine are correspondingly reduced according to a linear relation, and the cysteine fluorescent probe has high selectivity on cysteine, can distinguish cysteine from three biological mercaptans, and is suitable for being widely applied to detection of cysteine in living cells.
Triazole-gold (TAAu) catalyzed three-component coupling (A3 reaction) towards the synthesis of 2, 4-disubstituted quinoline derivatives
Zhang, Fusong,Lai, Qi,Shi, Xiaodong,Song, Zhiguang
supporting information, p. 392 - 394 (2018/06/04)
A gold-catalyzed three-component coupling reaction (A3 reaction) was developed as an efficient approach for the synthesis of challenging 2, 4-disubstituted quinoline derivatives. Compared to previously reported Cu/Au bi-catalyst system, this protocol enables achieving A3 reaction only in the presence of triazole-gold catalyst. Notably, 4-alkyl substituted or 2-alkyl substituted quinoline derivatives were obtained with good yields, which highlighted the unique advantage of this new strategy.
Method for constructing quinoline compound by means of functionalization of organic antimony catalyzed C-H bond
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Paragraph 0082; 0083, (2017/08/29)
The invention aims at developing a novel method for preparing a quinoline compound in a manner of high conversion rate and high yield from organic antimony frustrated lewis pair catalyst by means of C-H bond functionalization of imine and unsaturated hydr
Ytterbium pentafluorobenzoate as a novel fluorous Lewis acid catalyst in the synthesis of 2,4-disubstituted quinolines
Tang, Jun,Wang, Limin,Mao, Dan,Wang, Wenbo,Zhang, Liang,Wu, Shengying,Xie, Yongshu
supporting information; experimental part, p. 8465 - 8469 (2011/11/12)
A series of simple, efficient, stable and recoverable rare earth metal pentafluorobenzoates [RE(Pfb)3] have been synthesized for the first time. A highly efficient and environmentally friendly synthesis of 2,4-disubstituted quinolines catalyzed by Yb(Pfb)3 via one-pot reaction of aldehydes, alkynes and amines under solvent-free conditions has been explored.
