134435-90-8Relevant academic research and scientific papers
A New Approach to (Z)-Vinyloxyboranes via 1,4 Hydroboration of (E)-α,β-Unsaturated Ketones. Synthesis of syn Aldols
Boldrini, Gian Paolo,Mancini, Fabrizio,Tagliavini, Emilio,Trombini, Claudio,Umani-Ronchi, Achille
, p. 1680 - 1681 (2007/10/02)
(Z)-Vinyloxy boranes are obtained via 1,4-hydroboration of acyclic disubstituted (E)-α,β-unsaturated ketones with dicyclohexylborane or diisopinocampheylborane in tetrahydrofuran, CH2Cl2 or CHCl3 at 20 deg C; treatment of the hydroboration mixture with an aldehyde allows pure syn aldols to be synthesized in good yields, and in excellent enantiomeric excesses, using the latter borane.
