134457-74-2

Upstream product

• 134457-72-0 (5R)-(-)-<(1R)-1-(2,6-dichlorophenyl)ethyl>-5-(p-toluenesulfonyl)pyrrolidinone 
• 134527-63-2 (5S)-5-(2-but-3-enyl)-1-<(1R)-1-(2,6-dichlorophenyl)ethyl>pyrrolidinone 
• 126017-80-9 1-[(R)-1-(2,6-Dichloro-phenyl)-ethyl]-5-hydroxy-pyrrolidin-2-one 
• 134457-73-1 (5S,6R)-(-)-1-<(1R)-1-(2,6-dichlorophenyl)ethyl>-5-(4-hydroxybut-2-yl)pyrrolidinone 

Downstream Products

• 134457-75-3 (5S,6R)-(-)-5-(5,5-dimethoxypent-2-yl)-1-<(1R)-1-(2,6-dichlorophenyl)ethyl>pyrrolidinone 
• 134457-76-4 (2S,6)-(-)-2-(5,5-dimethoxypent-2-yl)-1-<(1R)-1-(2,6-dichlorophenyl)ethyl>pyrrolidine 

Relevant academic research and scientific papers

Enantioselective Total Synthesis of Indolizidine Alkaloids (-)-205A and (-)-235B

Enantioselective total syntheses of indolizidine alkaloids (-)-205A and (-)-235B are described.The syntheses proceed via a common late-stage intermediate, α-aminonitrile 1.Absolute stereochemical control over the C8 and C8a stereocenters in these material