134527-63-2

Upstream product

• 17486-12-3 (E)-but-2-en-1-yltrimethylsilane 
• 126017-80-9 1-[(S)-1-(2,6-Dichloro-phenyl)-ethyl]-5-hydroxy-pyrrolidin-2-one 
• 21969-32-4 crotylmagnesium chloride 
• 134457-72-0 (5R)-(-)-<(1R)-1-(2,6-dichlorophenyl)ethyl>-5-(p-toluenesulfonyl)pyrrolidinone 
• 126017-80-9 1-[(R)-1-(2,6-Dichloro-phenyl)-ethyl]-5-hydroxy-pyrrolidin-2-one 

Downstream Products

• 134457-83-3 5-sec-Butyl-1-((S)-1-phenyl-ethyl)-pyrrolidin-2-one 
• 134527-64-3 (5S,6S)-1-<(1R)-1-(2,6-dichlorophenyl)ethyl>-5-(4-hydroxybut-2-yl)pyrrolidinone 
• 134457-73-1 (5S,6R)-(-)-1-<(1R)-1-(2,6-dichlorophenyl)ethyl>-5-(4-hydroxybut-2-yl)pyrrolidinone 
• 134457-74-2 (5S,6R)-(-)-1<(1R)-1-(2,6-dichlorophenyl)ethyl>-5-(4-oxobut-2-yl)pyrrolidinone 
• 134457-76-4 (2S,6)-(-)-2-(5,5-dimethoxypent-2-yl)-1-<(1R)-1-(2,6-dichlorophenyl)ethyl>pyrrolidine 
• 134457-75-3 (5S,6R)-(-)-5-(5,5-dimethoxypent-2-yl)-1-<(1R)-1-(2,6-dichlorophenyl)ethyl>pyrrolidinone 

Relevant academic research and scientific papers

Enantioselective Total Synthesis of Indolizidine Alkaloids (-)-205A and (-)-235B

Enantioselective total syntheses of indolizidine alkaloids (-)-205A and (-)-235B are described.The syntheses proceed via a common late-stage intermediate, α-aminonitrile 1.Absolute stereochemical control over the C8 and C8a stereocenters in these material