1344667-72-6Relevant academic research and scientific papers
Regiospecific ortho-C?H Allylation of Benzoic Acids
Trita, A. Stefania,Biafora, Agostino,Pichette Drapeau, Martin,Weber, Philip,Goo?en, Lukas J.
, p. 14580 - 14584 (2018)
A carboxylate-directed ortho-C?H functionalization has been developed and it allows the regiospecific introduction of allyl residues to benzoic acids. In the presence of a [Ru(p-cymene)Cl2]2 and K3PO4, benzoic acids react with allyl acetates at only 50 °C to give the corresponding ortho-allylbenzoic acids. The protocol is generally applicable to both electron-rich and electron-poor benzoic acids in combination with linear and branched allyl acetates. The products can be further functionalized in situ, for example, by double-bond migration, lactonization, or decarboxylation.
Rhenium-catalyzed allylation of C-H bonds of benzoic and acrylic acids
Kuninobu, Yoichiro,Ohta, Kazuhiro,Takai, Kazuhiko
, p. 10791 - 10793 (2011/11/05)
We have succeeded in the allylation of aromatic and olefinic C-H bonds of benzoic and acrylic acids using a rhenium catalyst, Re2(CO) 10. In this reaction, isomerization of the introduced allyl group to the 1-propenyl group did not occur.
