1344736-16-8Relevant articles and documents
On the reactivity of imidazole carbamates and ureas and their use as esterification and amidation reagents
Heller, Stephen T.,Sarpong, Richmond
experimental part, p. 8851 - 8859 (2011/12/02)
The optimization, substrate scope, and mechanism of esterification and amidation of carboxylic acids mediated by imidazole-based reagents are discussed. The innate reactivity of carbonylimidazole reagents with a range of nucleophiles is also explored. New reagents developed for the synthesis of α,β-unsaturated esters are described, as are reagents for the preparation of tertiary amides directly from carboxylic acids.
