83395-39-5

Usage

Uses

Used in Chemical Synthesis Industry:
1H-Imidazole-1-carboxylicacid,2-propenylester(9CI) is used as a reagent for the preparation of allyl enol carbonate derivatives. It is achieved through a reaction with ketone enolates and boron trifluoride etherate, which allows for the synthesis of a variety of complex organic molecules with potential applications in pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Organic Chemistry Research:
In the field of organic chemistry, 1H-Imidazole-1-carboxylicacid,2-propenylester(9CI) serves as a valuable intermediate for the acylation of a mixture of primary and secondary alcohols. This process is crucial for the development of new synthetic routes and methodologies, as well as for the synthesis of bioactive compounds and novel materials.
Overall, 1H-Imidazole-1-carboxylicacid,2-propenylester(9CI) is a versatile compound with applications in chemical synthesis and research, making it an important molecule for the development of new chemical entities and processes.

Upstream product

• 288-32-4 1H-imidazole 
• 75-44-5 phosgene 
• 107-18-6 allyl alcohol 
• 2937-50-0 Allyl chloroformate 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 31410-01-2 1-allylimidazole 
• 21997-30-8 1-(prop-2-enyl)-1,2-dihydropyridine-2-one 
• 53603-13-7 allyl 2-(4-bromophenyl)acetate 
• 1344736-16-8 18(O)-allyl benzoate 
• 1047680-00-1 C₁₀H₁₀O₂Se 
• 22768-01-0 allyl benzyl carbonate 

Relevant academic research and scientific papers

Design and Synthesis of Cyclic Mismatch-Binding Ligands (CMBLs) with Variable Linkers by Ring-Closing Metathesis and their Photophysical and DNA Repeat Binding Properties

Cyclophane-containing bis(2-amino-1,8-naphthyridine) moieties attached to variable linkers at the C2-position (linker B) were synthesized as cyclic mismatch-binding ligands (CMBLs). Ring-closing metathesis (RCM) is used as a key step for the introduction

Synthesis method of imidazole additive

The invention relates to a synthesis method of an imidazole additive, and belongs to the technical field of battery electrolyte additives. The method comprises the following steps of: taking allyl alcohol or propargyl alcohol as a raw material, introducing phosgene at a speed of 40-50mL/min at a temperature of 0DEG C or below, controlling the reaction temperature to be less than 5DEG C in the process of introducing phosgene for reaction, performing heat preservation treatment for 20-30min after the reaction is finished, introducing nitrogen into a reaction kettle for 1-1.5h at room temperature, performing reduced pressure distillation and collecting fractions for later use; adding dichloromethane and imidazole into a reaction kettle, adding triethylamine into the reaction kettle at a rate of 90-100mL/min, introducing nitrogen to replace gas in the reaction kettle after adding is completed, raising the temperature to a reflux temperature, adding the collected fraction dropwise into the reaction kettle, performing stirring for 3-5h after dropwise adding is completed, conducting suction filtration, washing separated mother liquor with alkali liquor till the pH value is 7.2-7.3, and conducting drying and reduced pressure distillation to obtain a product. The method is simple in synthetic route, easy to operate, low in energy consumption and few in by-product.

Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation of Dihydroquinolinones

A palladium-catalyzed decarboxylative asymmetric allylic alkylation (Pd-DAAA) of benzo-fused and non-benzo-fused δ-valerolactams is disclosed. This methodology gives access to chiral lactams bearing C3-quaternary stereocenters, which are central to many n

NANOPARTICLES FOR DRUG DELIVERY

The invention provides therapeutic magnetic nanoparticles containing a therapeutic agent connected to a magnetic nanoparticle core through a stable functional group and a linker that can be induced to release the therapeutic agent from the core, through h

Studies on the enantioselective synthesis of carbazolones as intermediates in aspidosperma and kopsia alkaloid synthesis

Two strategies for the assembly of homochiral carbazolones have been investigated. The first exploited desymmetrisation of 1,3-cyclohexadione derivatives however this failed to deliver satisfactory outcomes. An orthogonal route exploiting palladium catalysed decarboxylative allylation of racemic carbazolone β-ketoesters has been developed. Herein we report full details on the development of this reaction and clarify apparent discrepancies between our preliminary reports and those of Shao.

On the reactivity of imidazole carbamates and ureas and their use as esterification and amidation reagents

The optimization, substrate scope, and mechanism of esterification and amidation of carboxylic acids mediated by imidazole-based reagents are discussed. The innate reactivity of carbonylimidazole reagents with a range of nucleophiles is also explored. New reagents developed for the synthesis of α,β-unsaturated esters are described, as are reagents for the preparation of tertiary amides directly from carboxylic acids.

Chemoselective esterification and amidation of carboxylic acids with imidazole carbamates and ureas

Imidazole carbamates and ureas were found to be chemoselective esterification and amidation reagents. A wide variety of carboxylic acids were converted to their ester or amide analogues by a simple synthetic procedure in high yields.

Synthesis of allyl selenides by palladium-catalyzed decarboxylative coupling

This communication details the Pd-catalyzed decarboxylation of selenocarbonates; use of a chiral nonracemic catalyst affords enantioenriched allyl selenides which undergo stereospecific [2,3]-sigmatropic rearrangements to form enantioenriched allylic amines and chlorides. The Royal Society of Chemistry.

The O-acylation of ketone enolates by allyl 1H-imidazole-1-carboxylate mediated with boron trifluoride etherate - A convenient procedure for the synthesis of substituted allyl enol carbonates

(Chemical Equation Presented) A convenient access to substituted allyl enol carbonates was established through the reaction of ketone enolates with the complex of allyl 1H-imidazole-1-carboxylates and boron trifluoride etherate.

Surface modification with orthogonal photosensitive silanes for sequential chemical lithography and site-selective particle deposition

(Chemical Equation Presented) Monolayer lithography: The concept of orthogonal cleavage of photolabile protecting groups was demonstrated with self-assembled silane layers on solid surfaces. Nitroveratryloxycarbonyl and benzoin derivatives can be addresse