83395-39-5Relevant articles and documents
Design and Synthesis of Cyclic Mismatch-Binding Ligands (CMBLs) with Variable Linkers by Ring-Closing Metathesis and their Photophysical and DNA Repeat Binding Properties
Mukherjee, Sanjukta,Dohno, Chikara,Nakatani, Kazuhiko
, p. 11385 - 11396 (2017)
Cyclophane-containing bis(2-amino-1,8-naphthyridine) moieties attached to variable linkers at the C2-position (linker B) were synthesized as cyclic mismatch-binding ligands (CMBLs). Ring-closing metathesis (RCM) is used as a key step for the introduction
Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation of Dihydroquinolinones
Trost, Barry M.,Nagaraju, Anugula,Wang, Feijun,Zuo, Zhijun,Xu, Jiayi,Hull, Kami L.
supporting information, (2019/03/19)
A palladium-catalyzed decarboxylative asymmetric allylic alkylation (Pd-DAAA) of benzo-fused and non-benzo-fused δ-valerolactams is disclosed. This methodology gives access to chiral lactams bearing C3-quaternary stereocenters, which are central to many n
Studies on the enantioselective synthesis of carbazolones as intermediates in aspidosperma and kopsia alkaloid synthesis
Gartshore, Christopher J.,Lupton, David W.
, p. 882 - 890 (2013/09/12)
Two strategies for the assembly of homochiral carbazolones have been investigated. The first exploited desymmetrisation of 1,3-cyclohexadione derivatives however this failed to deliver satisfactory outcomes. An orthogonal route exploiting palladium catalysed decarboxylative allylation of racemic carbazolone β-ketoesters has been developed. Herein we report full details on the development of this reaction and clarify apparent discrepancies between our preliminary reports and those of Shao.