134478-82-3Relevant academic research and scientific papers
Enantioselective allylation of aromatic amines after in situ generation of an activated cyclometalated iridium catalyst
Shu, Chutian,Leitner, Andreas,Hartwig, John F.
, p. 4797 - 4800 (2004)
Highly regio- and enantioselective allylation of aromatic amines is observed when a cyclometalated Ir-phosphoramidite complex is generated in situ (see scheme). The active catalyst can be formed from [{Ir(cod)Cl}2] and ligand L with a volatile alkylamine prior to addition of the reagents or upon use of a tertiary amine additive.
Direct palladium/carboxylic acid-catalyzed allylation of anilines with allylic alcohols in water
Yang, Shyh-Chyun,Hsu, Yi-Chun,Gan, Kim-Hong
, p. 3949 - 3958 (2007/10/03)
The direct activation of C-O bonds in allylic alcohols in water as a suspension medium by palladium complexes has been accelerated by carrying out the reactions in the presence of a carboxylic acid. The palladium-catalyzed allylation of anilines using allylic alcohols directly gave allylic anilines in good yields.
Observations on the intramolecular Heck reactions of aromatic chlorides using palladium/imidazolium salts
Caddick, Stephen,Kofie, William
, p. 9347 - 9350 (2007/10/03)
The intramolecular Heck reaction of aromatic amines and ethers using palladium/imidazolium salts is described. The use of tetra-n-butylammonium halide salts facilitates the reactivity of aromatic chlorides. An unexpected and novel palladium-mediated cyclisation is also described leading to the formation of a tricyclic adduct.
