134485-38-4

Upstream product

• 100-51-6 benzyl alcohol 
• 134485-30-6 ethyl-3,3-di(benzyl)oxypropanoate 

Downstream Products

• 134485-39-5 (E)-5,5-Bis-benzyloxy-pent-2-enoic acid ethyl ester 
• 134485-36-2 C₃₃H₃₁N₃O₆ 
• 134485-33-9 (2S,3S)-3-Azido-5,5-bis-benzyloxy-pentane-1,2-diol 
• 134485-32-8 [(2R,3R)-3-(2,2-Bis-benzyloxy-ethyl)-oxiranyl]-methanol 
• 188559-09-3 (2R,3R)-5,5-Bis-benzyloxy-1-trityloxy-pentane-2,3-diol 
• 188559-11-7 (2R,3R)-5,5-Bis-benzyloxy-1-methoxymethoxy-pentane-2,3-diol 
• 188559-32-2 4-Allyloxy-2-((2R,3R)-5-benzyloxy-2-trityloxymethyl-tetrahydro-furan-3-yloxy)-5-chloro-pyrimidine 
• 188559-30-0 4-Allyloxy-2-((2R,3R)-5-benzyloxy-2-trityloxymethyl-tetrahydro-furan-3-yloxy)-5-methyl-pyrimidine 
• 188559-31-1 4-Allyloxy-2-((2R,3R)-5-benzyloxy-2-trityloxymethyl-tetrahydro-furan-3-yloxy)-pyrimidine 
• 188559-37-7 2-((2R,3R)-5-Benzyloxy-2-trityloxymethyl-tetrahydro-furan-3-yloxy)-5-chloro-3H-pyrimidin-4-one 
• 188559-35-5 2-((2R,3R)-5-Benzyloxy-2-trityloxymethyl-tetrahydro-furan-3-yloxy)-5-methyl-3H-pyrimidin-4-one 
• 188559-36-6 2-((2R,3R)-5-Benzyloxy-2-trityloxymethyl-tetrahydro-furan-3-yloxy)-3H-pyrimidin-4-one 
• 188559-06-0 C₃₈H₃₆O₃ 
• 188559-34-4 4-Allyloxy-2-((2R,3R)-5-benzyloxy-2-methoxymethoxymethyl-tetrahydro-furan-3-yloxy)-5-fluoro-pyrimidine 

Relevant academic research and scientific papers

Stereocontrolled synthesis of β-2'-deoxypyrimidine nucleosides via intramolecular glycosylations

A pyrimidine moiety was tethered at the 3'-β-position of D-threo-furanosides. By carefully controlling the reaction conditions, pyrimidine bases can be delivered to the anomeric center to give of β-pyrimidine nucleosides in good yield and with complete stereocontrol.

Preparation of 3'-substituted-2',3'-dideoxynucleosides and 2'-deoxynucleosides from acyclic, achiral precursors

A process for the preparation of 3'-substituted-2',3'-dideoxynucleosides is provided that utilizes inexpensive, non-carbohydrate, acyclic, achiral starting materials and that proceeds with high enantiomeric and stereochemical control. The method can be used to prepare the pharmaceutically important compounds 3'-azido-3'-deoxythymidine, 3'-azido-2',3'-dideoxyuridine, 3'-fluoro-3'-deoxythymidine, and 3'-fluoro-3'-deoxyuridine.

An efficient synthesis of 3′-fluoro-3′-deoxythymidene (FLT)

A synthetic route which permits the regioselective introduction of fluoride into an FLT precursor under mild conditions and the subsequent conversion of that intermediate into FLT is reported.