1345017-07-3

Upstream product

• 1336938-63-6 (3-fluoro-4-methoxyphenyl)(p-toluenesulfonyl)methylisocyanide 
• 32024-14-9 3,5-diiodo-4-methoxybenzaldehyde 
• 74-89-5 methylamine 
• 351-54-2 3-fluoro-p-anisaldehyde 
• 1356537-07-9 C₁₆H₁₆FNO₄S 

Downstream Products

• 1345017-13-1 1-methyl-4-(3-fluoro-4-methoxyphenyl)-5-(3,5-diiodo-4-methoxyphenyl)imidazole hydrochloride 

Relevant academic research and scientific papers

COMBRETASTATIN ANALOGS FOR USE IN THE TREATMENT OF CANCER

The present invention relates to specific analogs of combretastatin, in particular the compounds of formula (I) as described and defined herein, and pharmaceutical compositions comprising the compounds, as well as their medical use, in particular in the treatment or prevention of cancer, including multidrug-resistant cancer.

Cytotoxic and antivascular 1-methyl-4-(3-fluoro-4-methoxyphenyl)-5- (halophenyl)-imidazoles

A series of 1-methyl-4,5-diphenylimidazoles 6 with various patterns of m-halogen substitution at the 5-phenyl ring were tested for cytotoxicity in cancer and nonmalignant cell lines and for their capacity to prevent tube formation in HUVEC cultures. Unlik