1345019-57-9Relevant academic research and scientific papers
Electrochemical synthesis and chemistry of chiral 1- cyanotetrahydroisoquinolines. An approach to the asymmetric syntheses of the alkaloid (-)-crispine A and its natural (+)-antipode
Louafi, Fadila,Moreau, Julie,Shahane, Saurabh,Golhen, Stephane,Roisnel, Thierry,Sinbandhit, Sourisak,Hurvois, Jean-Pierre
, p. 9720 - 9732 (2012/01/05)
The stereoselective convergent total syntheses of both enantiomers of the tetrahydroisoquinoline (THIQ) alkaloid crispine A are described. The THIQ precursors ( - )-6 (90:10 dr) and ( - )-11 (85:15 dr) were prepared from the alkylation - reduction sequenc
