134505-34-3

Basic information

• Product Name: 5-bromo-2-(4-methoxyphenyl)benzo-1,3-dioxole
• Synonyms: 5-bromo-2-(4-methoxyphenyl)benzo-1,3-dioxole
• CAS NO: 134505-34-3
• Molecular Weight: 307.144
• Mol File: 134505-34-3.mol

Chemical Properties

• CAS DataBase Reference: 5-bromo-2-(4-methoxyphenyl)benzo-1,3-dioxole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-(4-methoxyphenyl)benzo-1,3-dioxole(134505-34-3)
• EPA Substance Registry System: 5-bromo-2-(4-methoxyphenyl)benzo-1,3-dioxole(134505-34-3)

Safety Data

• Hazardous Substances Data: 134505-34-3(Hazardous Substances Data)

Upstream product

• 17345-77-6 1-bromo-3,4-dihydroxybenzene 
• 123-11-5 4-methoxy-benzaldehyde 
• 104-15-4 toluene-4-sulfonic acid 

Relevant articles and documents

Bicyclic derivatives

The invention concerns a bicyclic derivative of the formula I, or a pharmaceutically-acceptable salt thereof. wherein Ar1 is optionally substituted phenyl or naphthyl;, R1 if (1-6C)alkyl, (3-6C)alkenyl, (3-6C)alkynyl, cyano-(1-4C)alkyl or (2-4C)alkanoyl, or optionally substituted benzoyl; and, R2 and R3 together form a group of the formula -A1-X-A2-, wherein each of A1 and A2 is (1-4C)alkylene and X is oxy, thio, sulphinyl, sulphonyl or imino. The invention also concerns processes for the manufacture of a bicyclic derivative of the formula I, or a pharmaceutically-acceptable salt thereof, and pharmaceutical compositions containing said bicyclic derivatives. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.