Welcome to LookChem.com Sign In|Join Free

CAS

  • or

134507-62-3

134507-62-3

Post Buying Request

134507-62-3 Suppliers

Recommended suppliersmore

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

134507-62-3 Usage

Uses

A related compound of Cocaine (C633500), as substrate and inhibitor of plasma butyrylcholinesterase. Controlled substance.

Check Digit Verification of cas no

The CAS Registry Mumber 134507-62-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,5,0 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 134507-62:
(8*1)+(7*3)+(6*4)+(5*5)+(4*0)+(3*7)+(2*6)+(1*2)=113
113 % 10 = 3
So 134507-62-3 is a valid CAS Registry Number.

134507-62-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl (1S,3S,4R,5R)-3-(4-fluorobenzoyl)oxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

1.2 Other means of identification

Product number -
Other names methyl (1R,2R,3S,5S)-3-(4'-fluorobenzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:134507-62-3 SDS

134507-62-3Relevant articles and documents

Modulating cocaine vaccine potency through hapten fluorination

Cai, Xiaoqing,Tsuchikama, Kyoji,Janda, Kim D.

supporting information, p. 2971 - 2974 (2013/04/10)

Cocaine addiction is a long-lasting relapsing illness characterized by cycles of abuse, abstinence, and reinstatement, and antibody-based therapies could be a powerful therapeutic approach. Herein, we explored the possibility of using halogenated cocaine haptens to enhance the immunological properties of anti-cocaine vaccines. Three fluorine-containing cocaine haptens (GNF, GNCF and GN5F) and one chlorine-containing cocaine hapten (GNCl) were designed and synthesized, based upon the chemical scaffold of the only hapten that has reached clinical trials, succinyl norcocaine (SNC). Hapten GNF was found to retain potent cocaine affinity, and also elicit antibodies in a higher concentration than the parent structure SNC. Our data suggests that not only could strategic hapten fluorination be useful for improving upon the current cocaine vaccine undergoing clinical trials, but it may also be a valuable new approach, with application to any of the vaccines being developed for the treatment of drugs of abuse.