1345096-79-8

Basic information

• Product Name: 3-(2-hydroxybenzoyl)-1-methylquinolin-2(1H)-one
• Synonyms: 3-(2-hydroxybenzoyl)-1-methylquinolin-2(1H)-one
• CAS NO: 1345096-79-8
• Molecular Weight: 279.295
• Mol File: 1345096-79-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(2-hydroxybenzoyl)-1-methylquinolin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-hydroxybenzoyl)-1-methylquinolin-2(1H)-one(1345096-79-8)
• EPA Substance Registry System: 3-(2-hydroxybenzoyl)-1-methylquinolin-2(1H)-one(1345096-79-8)

Safety Data

• Hazardous Substances Data: 1345096-79-8(Hazardous Substances Data)

Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 579-72-6 2-(dimethylamino)benzaldehyde 
• 38518-76-2 2-amino-4H-1-benzopyran-4-one 
• 445291-56-5 2-(N-methyl-N-phenyl)aminochromone-3-carboxaldehyde 
• 213273-03-1 4-oxo-2-(N-phenyl)amino-4H-chromene-3-carbaldehyde 
• 113326-75-3 C-(4-oxo-4H<1>benzopyran-3-yl)-N-phenylnitrone 
• 17422-74-1 3-Formylchromone 

Relevant articles and documents

Redox-Triggered Switchable Synthesis of 3,4-Dihydroquinolin-2(1 H)-one Derivatives via Hydride Transfer/ N-Dealkylation/ N-Acylation

The switchable synthesis of 3-non, 3-mono, 3,3′-disubstituted 3,4-dihydroquinolin-2(1H)-ones was developed through a redox-neutral hydride-transfer/N-dealkylation/N-acylation strategy from o-aminobenzaldehyde with 4-hydroxycoumarin, and Meldrum's acid, respectively. The unprecedented strategy for the synthesis of 3,3′-highly functionalized 3,4-dihydroquinolin-2(1H)-one has been realized with the in situ utilization of the released HCHO via the o-QM involved Michael addition. In addition, the synthetic utility of this protocol has been well illustrated via concise synthesis of CYP11B2 inhibitor.

A one-pot rearrangement of 2-(N-Alkyl-N-aryl)aminochromone-3-carbaldehyde to N-Alkyl-3-salicyloyl-2-quinolone - An antileishmanial agent

2-(N-Aryl)aminochromone-3-carbaldehyde does not show any change on heating in acetic acid, but under the same reaction conditions 2-(N-alkyl-N-aryl) aminochromone-3-carbaldehyde rearranges to 3-salicyloyl-2-quinolones, which exhibits antileishmanial activ