38518-76-2

Usage

Uses

Used in Biochemical Assays and Fluorescent Labeling:
2-Amino-4H-1-benzopyran-4-one is used as a fluorescent probe for the study of proteins, enabling researchers to track and visualize protein interactions, localization, and dynamics within biological systems.
Used in Detection of Lipoproteins:
2-Amino-4H-1-benzopyran-4-one is used as a detection probe for lipoproteins, aiding in the analysis and quantification of these important blood components, which are crucial for lipid transport and metabolism.
Used in High-Performance Liquid Chromatography (HPLC):
2-Amino-4H-1-benzopyran-4-one is employed as a fluorophore in HPLC, enhancing the sensitivity and specificity of the technique for the separation and detection of various compounds in complex mixtures.
Used in Synthesis of Fluorescent Dyes and Optical Brighteners:
As a derivative of coumarin, 2-Amino-4H-1-benzopyran-4-one is used in the synthesis of fluorescent dyes and optical brighteners, which have applications in various industries, including textiles, paper manufacturing, and cosmetics, to improve the appearance and properties of products.

Upstream product

• 23462-75-1 5,6-dihydro-2H-pyran-3(4H)-one 
• 61424-76-8 2-amino-3-formylchromone 
• 61348-47-8 5-(2-hydroxyphenyl)isoxazole 
• 51070-14-5 4H-1-benzopyranol[3,4-d]isoxazol-4-one 
• 53658-17-6 (2-hydroxyphenyl)-(1,2-oxazol-4-yl)methanone 
• 917373-44-5 4-oxo-2-(trifluoromethyl)-4H-chromene-3-carbonitrile 
• 106129-86-6 1-(2-hydroxyphenyl)-3-dimethylaminoprop-2-enone 
• 1006-67-3 5-phenylisoxazole 
• 118-93-4 o-hydroxyacetophenone 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 75-05-8 acetonitrile 
• 69-72-7 salicylic acid 
• 75825-81-9 4-(o-hydroxybenzoyl)-isoxazole oxime 

Downstream Products

• 17831-88-8 4-chloro-2H-1-benzopyran-2-one 
• 10523-64-5 2-(5-amino-1H-pyrazol-3-yl)phenol 

Relevant academic research and scientific papers

Synthesis of Chromeno[2,3-d]pyrimidin-5-one Derivatives from 1,3,5-Triazinanes via Two Different Reaction Pathways

1,3,5-Triazinanes, as a kind of versatile building block, are applied in the synthesis of chromeno[2,3-d]pyrimidin-5-one derivatives via two different reaction modes, which perfectly exhibits the powerful function of 1,3,5-triazinane as a three-atom synth

CuI/Cu(OSO2CF3)2 catalysed convenient approach to dichromenopyridines and triazole-thiazole appended chromone derivatives

A variety of new pentacyclic dichromenopyridines have been synthesized from 2-amino chromone and O-propargyloxy salicilaldehydes through intramolecular Povarov reaction using CuI/Cu(OSO2CF3)2 as a Lewis acid catalyst. The

Zn(OTf)2-Catalyzed Formal [3 + 3] Cascade Annulation of Propargylic Alcohols with 2-Aminochromones: Accessing the Chromeno[2,3- b]pyridines

A Zn(OTf)2-catalyzed formal [3 + 3] cascade annulation strategy for the synthesis of functionalized chromeno[2,3-b]pyridines has been developed using propargylic alcohols and 2-aminochromones as the substrates. The protocol provides a convenien

Chromenone-rhodamine conjugate for naked eye detection of Al3+ and Hg2+ ions in semi aqueous medium

Chromenone-rhodamine conjugate 1 has been synthesized and its metal ion binding properties have been studied in CH3CN/water (3:1, v/v; 10?mM HEPES buffer; pH?=?6.85). Compound 1 senses multiple metal ions such as Al3+ and Hg2+/

Synthesis of unsymmetrical 4-oxo-2-vinyl-4H-chromene-3-carbonitrile dyes via Knoevenagel reaction

New 4-oxo-2-vinyl-4H-chromene-3-carbonitrile derivatives have been synthesized by the Knoevenagel reaction of 2-methyl-4-oxo-4H-chromene-3-carbonitrile with aromatic and heteroaromatic aldehydes. Spectral properties of the obtained compounds have been studied.

Difluoromethylthiolation of Phenols and Related Compounds with a HF2CSO2Na/Ph2PCl/Me3SiCl System

A novel HF2CSO2Na/Ph2PCl/Me3SiCl system is disclosed for the late-stage direct difluoromethylthiolation of Csp2 and Csp3 nucleophiles. Difluoromethylthiolation of phenols and naphthols proceeded nicely under this system to regioselectively provide corresponding SCF2H compounds in good yields. Other substrates such as indoles, pyrroles, pyrazoles, enamines, ketones, and β-keto esters were also transformed to corresponding SCF2H products in good yields. The late-stage direct difluoromethylthiolation of a number of natural products and pharmaceutically attractive molecules was also achieved.

A Convenient and Practical Synthesis of Aminopyrazoles

A selective methodology for preparing highly substituted aminopyrazoles has been demonstrated. Starting with an acetophenol core, the corresponding substituted isoxazole is prepared in two steps. The isoxazole is transformed into a benzopyran. Alkylation

Convenient synthesis of chromones and quinolinones

A one pot synthesis of substituted chromones and quinolinones by condensing commercially available and cheaper molecules like salicylic acid and anthranilic acid respectively with alkenes / nitriles followed by insitu cyclization using ammonium acetate as base has been achieved.

Reactions of 3-(polyfluoroacyl)chromones with hydroxylamine: synthesis of novel RF-containing isoxazole and chromone derivatives

Reaction of 3-(polyfluoroacyl)chromones with hydroxylamine free base proceeds via nucleophilic 1,4-addition followed by opening of the pyrone ring and subsequent cyclization to 4-(polyfluoroalkyl)-4H-chromeno[3,4-d]isoxazol-4-ols in good yields. On treatm

Synthesis of 2,2′-diaminobischromones using a modified procedure for the rearrangement of 5-(2-hydroxyphenyl)isoxazole to 2-aminochromone

A modified procedure for the rearrangement of 5-(2-hydroxyphenyl)isoxazoles 6a-e to 2-aminochromones 8a-e was developed and this procedure was utilised in the synthesis of hitherto unreported bischromones 3a-c. The isoxazoles 6a-e were prepared regioselec