134541-03-0 Usage
Uses
Used in Pharmaceutical Synthesis:
5-Ethyl-isoxazole-4-carboxylic acid is used as a key intermediate in the synthesis of pharmaceuticals for its ability to enhance the biological activity of drug molecules. Its unique structure allows for the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Development:
In the agrochemical industry, 5-ethyl-isoxazole-4-carboxylic acid is utilized as a building block for the creation of novel agrochemicals, such as insecticides, herbicides, and fungicides. Its incorporation into these compounds can lead to enhanced pest control and crop protection.
Used in Polymer and Material Science:
5-Ethyl-isoxazole-4-carboxylic acid is employed in the development of new polymers and materials, where its heterocyclic structure contributes to the desired properties of the final product. This includes applications in coatings, adhesives, and other industrial materials.
Used in Medicinal Chemistry Research:
5-Ethyl-isoxazole-4-carboxylic acid has potential applications in the field of medicinal chemistry due to its biological activities. Researchers are interested in its use as a target for drug discovery and development, as it may lead to the creation of new therapeutic agents with novel mechanisms of action.
Overall, 5-ethyl-isoxazole-4-carboxylic acid is a valuable chemical compound with diverse applications across various industries, including pharmaceuticals, agrochemicals, polymer and material science, and medicinal chemistry research. Its unique structure and properties make it an essential component in the development of innovative products and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 134541-03-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,5,4 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 134541-03:
(8*1)+(7*3)+(6*4)+(5*5)+(4*4)+(3*1)+(2*0)+(1*3)=100
100 % 10 = 0
So 134541-03-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H7NO3/c1-2-5-4(6(8)9)3-7-10-5/h3H,2H2,1H3,(H,8,9)
134541-03-0Relevant academic research and scientific papers
For the prevention and treatment of various autoimmune diseases of the new compound
-
, (2018/04/20)
Disclosed is an isoxazole derivative that inhibits the activity of the Janus kinases (JAKs), the structure thereof as presented in formula I, formula II, formula IX, and formula XI. The substituent groups in the formulas are described in the description. Also disclosed are the pharmaceutical composition of the compound and a related use in medicine preparation.
Reaction of 2-Dimethylaminomethylene-1,3-diones with Dinucleophiles. X. Synthesis of 5-Substituted Ethyl or Methyl 4-Isoxazolecarboxylates and Methyl 4-(2,2-Dimethyl-1-oxopropyl)-5-isoxazolecarboxylate
Schenone, Pietro,Fossa, Paola,Menozzi, Giulia
, p. 453 - 457 (2007/10/02)
Reaction of ethyl or methyl 2-dimethylaminomethylene-3-oxoalkanoates with hydroxylamine hydrochloride in methanol solution afforded in high yields the relative esters of 5-substituted 4-isoxazolecarboxylic acids II.These esters were hydrolyzed generally with concentrated hydrochloric acid-acetic acid mixtures to the corresponding carboxylic acids in satisfactory yields.Ethyl or methyl esters II isomerized with sodium ethoxide or methoxide, respectively, to the corresponding esters or hemiesters of 2-cyano-3-oxoalkanoic acids generally in excellent to satisfactory yields.Reaction of methyl 5,5-dimethyl-3-dimethylaminomethylene-2,4-dioxohexanoate with hydroxylamine hydrochloride afforded in moderate yield methyl 4-(2,2-dimethyl-1-oxopropyl)-5-isoxazolecarboxylate, which was converted by acid hydrolysis as above to 4-t-butyl-4-hydroxyfuroisoxazol-6-(4H)-one.
