1345447-21-3

Upstream product

• 75-52-5 nitromethane 

Downstream Products

• 1345440-61-0 C₂₆H₂₀F₂N₆O₄ 
• 1610680-66-4 2-(4-(8-amino-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile 
• 1610680-65-3 2-methyl-2-(4-(3-methyl-8-morpholino-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)propanenitrile 
• 1610681-27-0 3-methyl-1-phenyl-1H-imidazo[4,5-c]quinolin-2(3H)-one 
• 1610681-26-9 3,8-dimethyl-1-phenyl-1H-imidazo[4,5-c]quinolin-2(3H)-one 
• 1610681-25-8 4-(3-methyl-2-oxo-1-(p-tolyl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-8-yl)benzoic acid 
• 1201646-92-5 2-(4-((3'-amino[3,6'-biquinolin]-4'-yl)amino)phenyl)-2-methyl propanenitrile 
• 1610680-64-2 2-methyl-2-(4-(3-methyl-8-(4-methylpiperazin-1-yl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)propanenitrile 
• 1610681-24-7 1-(4-(dimethylamino)phenyl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one 
• 1610681-21-4 2-(4-(2-oxo-8-(pyridin-4-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)acetonitrile 
• 1610681-23-6 4-(2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)benzonitrile 
• 1610681-18-9 3-methyl-1-(4-morpholinophenyl)-8-(pyridin-4-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one 
• 1610681-17-8 1-(4-(dimethylamino)phenyl)-3-methyl-8-(pyridin-4-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one 
• 1610681-16-7 1-(4-methoxyphenyl)-3-methyl-8-(pyridin-4-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one 

Relevant academic research and scientific papers

HETEROCYCLIC CARBOXYLIC ACID AMIDES AS PDK1 INIHIBITORS

The present invention encompasses compounds of general formula (1) wherein the groups R1 to R4, Qa, Qb, QH, L and n are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations which contain such compounds and their use as medicaments.

1H - IMIDAZO [4, 5 - C] QUINOLINES

The present invention encompasses compounds of general formula (1), wherein the groups R1 to R7, Qa, Qb, L, n and m are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations containing such compounds and their use as medicaments.