13455-81-7

Basic information

• Product Name: 2-Butenoic acid, 3-(4-chlorophenyl)-2-cyano-, ethyl ester
• Synonyms: 2-Butenoic acid, 3-(4-chlorophenyl)-2-cyano-, ethyl ester
• CAS NO: 13455-81-7
• Molecular Formula: C₁₃H₁₂ClNO₂
• Molecular Weight: 249.69288
• Mol File: 13455-81-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Butenoic acid, 3-(4-chlorophenyl)-2-cyano-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenoic acid, 3-(4-chlorophenyl)-2-cyano-, ethyl ester(13455-81-7)
• EPA Substance Registry System: 2-Butenoic acid, 3-(4-chlorophenyl)-2-cyano-, ethyl ester(13455-81-7)

Safety Data

• Hazardous Substances Data: 13455-81-7(Hazardous Substances Data)

Upstream product

• 99-91-2 para-chloroacetophenone 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 117489-26-6 4-(4-Chloro-phenyl)-2-oxo-1,6-diphenyl-1,2,5,6-tetrahydro-pyridine-3-carbonitrile 
• 893802-40-9 5-(4-chlorophenyl)-2-(pyridin-2-yl)thieno[2,3-d]pyrimidin-4(3H)-one 
• 724745-81-7 5-(4-chloro-phenyl)-2-(pyridin-3-yl)thieno[2,3-d]pyrimidin-4(3H)-one 
• 792952-19-3 5-(4-chloro-phenyl)-2-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4(3H)-one 
• 65234-09-5 ethyl 2-amino-4-chlorophenyl-thiophene-3-carboxylate 
• 92165-23-6 ethyl 3-(4-chlorophenyl)-2,3-dicyanobutanoate 
• 91241-42-8 2-(4-Chlor-phenyl)-2-methyl-bernsteinsaeure 
• 4173-00-6 α-Methyl-α-(4-chlor-phenyl)-bernsteinsaeure-dinitril 
• 95422-28-9 4-<4-Chlor-phenyl>-4-methyl-pimelinsaeure-diaethylester 
• 93089-25-9 3-<4-Chlor-phenyl>-3-methyl-glutarsaeure-diaethylester 
• 92294-96-7 4-<4-Chlor-phenyl>-4-methyl-pimelinsaeure 
• 92194-57-5 3-<4-Chlor-phenyl>-3-methyl-1.5-dicyan-pentan 
• 91766-78-8 3-(4-Chlorphenyl)-3-methyl-1,5-dibrom-pentan 
• 91561-81-8 3-<4-Chlor-phenyl>-3-methyl-1,5-dihydroxy-pentan 

Relevant articles and documents

Amine-functionalized Metal-Organic Frameworks: An Efficient and Recyclable Heterogeneous Catalyst for the Knoevenagel Condensation Reaction

A highly efficient and reusable catalyst based on metal-organic frameworks (MOF) has been synthesized by post-functionalization and applied in Knoevenagel condensations of various aldehydes and ketones. The catalytic efficiency was demonstrated by the hig

A facile microwave-assisted Knoevenagel condensation of various aldehydes and ketones using amine-functionalized metal organic frameworks

An amine-functionalized metal organic framework (MOF) was used as highly efficient and recyclable heterogeneous catalyst for Knoevenagel condensation of various aromatic aldehydes and ketones in ethanol. The catalytic efficiency was demonstrated by the hi

Synthesis and antimicrobial activity of novel 2-(pyridin-2-yl)thieno[2,3-d] pyrimidin-4 (3H)-ones

In the present study, some new 2-(pyridin-2-yl)thieno[2,3-d]pyrimidin-4(3H) -ones derivatives (IIa-o) were synthesized. The target compounds (IIa-o) were synthesized through the acid catalyzed condensation of 2-cyano, 3-cyano, and 4-cyano-pyridines with various 2-amino-3-carbethoxythiophenes (Ia-e). All thiophene derivatives were synthesized by Gewald reaction. The structures of the newly synthesized compounds were confirmed by UV-Visible, FT-IR, 1H-NMR, and mass spectral studies. All synthesized compounds were evaluated for their antimicrobial activity against various gram-positive and gram-negative bacterial and fungal strains. Amongst the synthesized compounds IIa, IIb, IId, IIe, and IIm were found to be active. TUeBITAK.