13456-84-3Relevant articles and documents
A new coupling reaction of propargyl carbonates mediated by Ti(OiPr)2Cl2/Mg
Yang, Fanglong,Zhao, Gang,Ding, Yu,Zhao, Zongbao,Zheng, Yueqing
, p. 1289 - 1293 (2002)
A new homocoupling reaction of 1,1-disubstituted propargyl carbonates or 1-monosubstituted propargyl carbonates, mediated by Ti(OiPr)2Cl2/Mg in ether at 0°C, was found to form symmetric 1,5-hexadiynes and 1-allenyl-5-ynes in moderate
A highly efficient, practical, and general route for the synthesis of (R3P)2Pd(0): Structural evidence on the reduction mechanism of Pd(II) to Pd(0)
Li, Hongbo,Grasa, Gabriela A.,Colacot, Thomas J.
, p. 3332 - 3335 (2010)
(Equation Presented). A highly efficient, practical, and general method was developed to synthesize a family of (R3P)2Pd(0) complexes, using a stoichiometric amount of phosphine ligands and readily available Pd(II) precursors. The st
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Hurd,Jones
, p. 1924,1925 (1934)
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One-pot Sonogashira–Hydroarylation reaction catalyzed by anionic palladium complexes in an aqueous medium
Dziadas, M.,Trzeciak, A. M.,Wójcik, E.
supporting information, (2022/01/26)
It was found that anionic Pd(II) complexes of type [CA]2[PdCl4] and [CA]2[Pd2Cl6] (CA = imidazolium or pyridinium cation) are effective catalysts for copper-free Sonogashira coupling in an aqueous med
Copper-Catalyzed Radical 1,4-Difunctionalization of 1,3-Enynes with Alkyl Diacyl Peroxides and N-Fluorobenzenesulfonimide
Zhu, Xiaotao,Deng, Weili,Chiou, Mong-Feng,Ye, Changqing,Jian, Wujun,Zeng, Yuehua,Jiao, Yihang,Ge, Liang,Li, Yajun,Zhang, Xinhao,Bao, Hongli
, p. 548 - 559 (2019/01/04)
Many reactions involving allenyl ion species have been studied, but reactions involving allenyl radicals are less well understood, perhaps because of the inconvenience associated with the generation of short-lived allenyl radicals. We describe here a versatile method for the generation of allenyl radicals and their previously unreported applications in the intermolecular 1,4-carbocyanation and 1,4-sulfimidocyanation of 1,3-enynes. With the assistance of the trifunctional reagents, alkyl diacyl peroxides or N-fluorobenzenesulfonimide, a range of synthetically challenging multisubstituted allenes can be prepared with high regioselectivity. These multisubstituted allenes can be easily transformed into synthetically useful structures such as fluorinated vinyl cyanides, lactones, functionalized allenyl amides, 1-aminonaphthalenes, and pyridin-2(1H)-ones, and several novel transformations are reported. The results of radical scavenger and radical clock experiments are consistent with the proposed allenyl radical pathway. Density functional theory (DFT) and IR spectroscopy studies suggest the formation of an isocyanocopper(II) species in the ligand exchange step. On the basis of the results of IR, DFT, and diastereoselectivity studies, an isocyanocopper(II)/copper(I) catalytic cycle is proposed, which differs from the previously considered Cu(III) mechanism in cyanation reactions.
Copper-catalyzed silylation reactions of propargyl epoxides: Easy access to 2,3-allenols and stereodefined alkenes
Chang, Xi-Hao,Liu, Zheng-Li,Luo, Yun-Cheng,Yang, Chao,Liu, Xiao-Wei,Da, Bing-Chao,Li, Jie-Jun,Ahmad, Tanveer,Loh, Teck-Peng,Xu, Yun-He
, p. 9344 - 9347 (2017/08/23)
Efficient silylation reactions of propargyl epoxides catalyzed by copper catalysts have been developed. Under mild reaction conditions, tri- and tetra-substituted functionalized allenols and alkenes could be selectively obtained in moderate to high yields
