134563-22-7 Usage
General Description
"(R)-Benzyl 2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate" is a chemical compound with a complex structure, often used in various chemical research and development applications. While specific properties and usage of this compound may vary, like other pyrrolidines, it often forms part of larger molecules in pharmacological compounds due to the nitrogen present in its structure. The molecule includes a benzyl group, which consists of a phenyl group attached to a methylene bridge - common in various organic compounds. Additionally, two carboxylate groups are present, which contribute to the acidity of the compound. Notably, its "(R)-" designation indicates this compound's specific spatial arrangement, as various molecules can exist in multiple forms, referred to as stereoisomers.
Check Digit Verification of cas no
The CAS Registry Mumber 134563-22-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,5,6 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 134563-22:
(8*1)+(7*3)+(6*4)+(5*5)+(4*6)+(3*3)+(2*2)+(1*2)=117
117 % 10 = 7
So 134563-22-7 is a valid CAS Registry Number.
InChI:InChI=1/C17H22N2O3/c20-16(18-10-4-5-11-18)15-9-6-12-19(15)17(21)22-13-14-7-2-1-3-8-14/h1-3,7-8,15H,4-6,9-13H2
134563-22-7Relevant articles and documents
AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS
-
Page 98, (2010/02/08)
Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.
Structure activity relationship of inhibitors specific for prolyl endopeptidase.
Yoshimoto,Tsuru,Yamamoto,Ikezawa,Furukawa
, p. 37 - 43 (2007/10/02)
Structural requirements of N-blocked L-proline derivatives as specific inhibitors for prolyl endopeptidase were investigated using a series of substrate analogs. Replacement of L-proline by its D-isomer remarkably reduced the inhibition. Introduction of a sulfur atom in proline and/or in the penultimate pyrrolidine rings significantly increased the inhibition, but the introduction of oxygen rather diminished the activity. A peptide linkage (acid-amide bond) between the proline and the pyrrolidine ring was also required to keep the inhibitory activity. A benzyloxycarbonyl group was most effective as an N-blocked component of the inhibitors.
