1345688-71-2

Upstream product

• 14028-67-2 N-acetyl-1,2,3,4-tetrahydroisoquinoline 
• 1345688-34-7 1-(2-acetyl-1,2,3,4-tetrahydroisoquinolin-7-yl)-4-[4-(4-chlorophenyl)piperidin-1-yl]butan-1-one 
• 1345688-29-0 1-(2-acetyl-1,2,3,4-tetrahydroisoquinolin-7-yl)-4-chlorobutan-1-one 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Melanin-concentrating hormone receptor 1 antagonists: Synthesis, structure-activity relationship, docking studies, and biological evaluation of 2,3,4,5-tetrahydro-1H-3-benzazepine derivatives

Melanin-concentrating hormone receptor 1 (MCHR1) antagonists have been studied as potential agents for the treatment of obesity. Initial structure-activity relationship studies of in-house hit compound 1a and subsequent optimization studies resulted in th