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14366-73-5 Usage

General Description

1-chloro-4-[(2-chloroethyl)thio]benzene is a chemical compound that consists of a benzene ring with a chlorine atom attached at the 1 position and a 2-chloroethyl thioether group attached at the 4 position. 1-chloro-4-[(2-chloroethyl)thio]benzene is a colorless liquid with a strong, pungent odor. It is primarily used as an intermediate in the production of pharmaceuticals, dyes, and agrochemicals. Additionally, it is used as a solvent in chemical reactions and as a reagent in organic synthesis. 1-chloro-4-[(2-chloroethyl)thio]benzene is flammable and may cause skin and eye irritation upon contact. It is important to handle this chemical with care and follow proper safety precautions when working with it.

Check Digit Verification of cas no

The CAS Registry Mumber 14366-73-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,6 and 6 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 14366-73:
105 % 10 = 5
So 14366-73-5 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017


1.1 GHS Product identifier

Product name 1-chloro-4-(2-chloroethylsulfanyl)benzene

1.2 Other means of identification

Product number -
Other names 2-chloroethyl 4-chlorophenyl sulphide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14366-73-5 SDS

14366-73-5Relevant articles and documents

Synthesis of a new class of arylsulfonylethylsulfonylmethyloxazolines and thiazolines

Padmavathi, Venkatapuram,Venkatesh, Bhumireddy Chinnachennaiahgari,Premakumari, Chokkappagari,Padmaja, Adivireddy

scheme or table, p. 646 - 651 (2012/09/07)

A new class of arylsulfonylethylsulfonylmethyl oxazolines and thiazolines were prepared using multistep, one-pot methodologies exploiting lanthanide alkoxides and under microwave irradiation. The microwave method provides an excellent approach in a single step with high yields.



, (2008/06/13)

Selective MMP-13 inhibitors are fused pyrimidinones of the formula or a pharmaceutically acceptable salt thereof, wherein: W, together with the carbon atoms to which it is attached, form a 5-membered ring diradical X is O, S, SO, SO2, NR5, or CH 2; B is O or NR5; or A and B are taken together to form--C≡C--; R1, R4, and R 5 are hydrogen, alkyl, alkenyl, alkynyl, (CH2)n aryl, (CH2)n cycloalkyl, C1-C6 alkanoyl, or (CH2)n heteroaryl; R2 and R3 are hydrogen, alkyl, alkenyl, alkynyl CN, NO2, NR 4R5, (CH2)n cycloalkyl, (CH2) n aryl, or (CH2)n heteroaryl; R2 may further be halo; n is an integer of from 0 to 5; and R4 and R5 when taken together with a nitrogen to which they are both attached complete a 3-to 8-membered ring containing carbon atoms and optionally containing O, S, or N, and substituted or unsubstituted; with the proviso that R1 and R3 are not both selected from hydrogen and C1-C6 alkyl.


El-Khawaga, A. M.,El-Zohry, M. F.,Ismail, M. T.,Abdel-Wahab, A. A.,Khalaf, A. A.

, p. 265 - 270 (2007/10/02)

The feasibility of cycloalkylation reactions in the presence of Friedel-Crafts catalysts was demonstrated in a nimber of aryl hydroxyalkyl sulfides (1-5), and benzyl hydroxyalkyl sulfides (6-7).Treatment of compounds (1-7) with Friedel-Crafts catalysts gave diaryl disulfides, diaryl sulfides, arene thiols, chlorohydrins, aryl chloroalkyl sulfides, aryl alkenyl sulfides and cyclization products.It is noteworthy to mention that cyclization products were isolated only in cases where the hydroxyl group is linked to a tertiary carbon atom as in compounds 3 and 7.A suitable reaction pathway is suggested to rationalize the formation of the various reaction products.

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