1345714-77-3

Basic information

• Product Name: C₁₂H₁₃ClO₃
• Synonyms: C₁₂H₁₃ClO₃
• CAS NO: 1345714-77-3
• Molecular Weight: 240.686
• Mol File: 1345714-77-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₃ClO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₃ClO₃(1345714-77-3)
• EPA Substance Registry System: C₁₂H₁₃ClO₃(1345714-77-3)

Safety Data

• Hazardous Substances Data: 1345714-77-3(Hazardous Substances Data)

Upstream product

• 54109-03-4 5-chloro-3H-isobenzofuran-1-one 
• 98216-82-1 5-chloro-1,3-dihydroisobenzofuran-1-ol 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 1345714-81-9 (E)-ethyl 3-(4-chloro-2-formylphenyl)acrylate 

Relevant articles and documents

Squaramide-catalyzed asymmetric intramolecular oxa-michael reaction of α,β-unsaturated carbonyls containing benzyl alcohol: Construction of chiral 1-substituted phthalans

Organocatalytic enantioselective intramolecular oxa-Michael reactions of benzyl alcohol bearing α,β-unsaturated carbonyls as Michael acceptors are presented herein. Using cinchona squaramide-based organocatalyst, enones as well as α,βunsaturated esters containing benzyl alcohol provided their corresponding 1,3-dihydroisobenzofuranyl-1-methylene ketones and 1,3-dihydroisobenzofuranyl-1-methylene esters in excellent yields with high enantioselectivities. In addition, enantioenriched 1,3-dihydroisobenzofuranyl-1-methylene ketone could be obtained from the Wittig/oxa-Michael reaction cascade of 1,3-dihydro-2-benzofuran-1-ol.