1345732-51-5

Basic information

• Product Name: 3-(2-(4-(3-methoxybenzoyl)piperazin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
• Synonyms: 3-(2-(4-(3-methoxybenzoyl)piperazin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
• CAS NO: 1345732-51-5
• Molecular Weight: 410.516
• Mol File: 1345732-51-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-(4-(3-methoxybenzoyl)piperazin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-(4-(3-methoxybenzoyl)piperazin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one(1345732-51-5)
• EPA Substance Registry System: 3-(2-(4-(3-methoxybenzoyl)piperazin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one(1345732-51-5)

Safety Data

• Hazardous Substances Data: 1345732-51-5(Hazardous Substances Data)

Upstream product

• 41078-70-0 3-(2-chloro-ethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 
• 63234-88-8 2-methyl-3-(2-(piperazin-1-yl)ethyl)-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one 
• 1711-05-3 m-anisoyl chloride 
• 380634-63-9 3-(1-(pyridin-2-ylamino)ethylidene)dihydrofuran-2-(3H)-one 
• 63234-80-0 3-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one 
• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 
• 504-29-0 2-aminopyridine 

Relevant articles and documents

Synthesis of 2-methyl-3-(2-(piperazin-1-yl)ethyl)-6,7,8,9-tetrahydro- 4hpyrido[1,2-a]pyrimidin-4-one derivatives as antimicrobial agents

A series of novel 2-methyl-3-(2-(piperazin-1-yl)ethyl)-6,7,8,9-tetrahydro- 4H-pyrido[1,2-a]pyrimidin-4-one sulfonamide and carboxamide derivatives were synthesized in good yield. The synthesized compounds were characterized by 1H-NMR, FTIR and elemental analysis. All the synthesised compounds were screened for their in vitro antimicrobial activity by agar well diffusion and micro dilution method against standard strains of Gram-positive (Bacillus subtilis MTCC 121, Staphylococcus epidermidis 435), and Gram-negative (Xanthomonas campestris 7903 and Pseudomonas aeruginosa MTCC 7908) bacteria. Compound 7a and compound 8d with dichloro substitution among sulphonamide and carboxamide series respectively showed potent inhibitory activity.