134575-38-5

Basic information

• Product Name: (1R,5S,6s)-3-benzyl 6-ethyl 3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate
• Synonyms: (1R,5S,6s)-3-benzyl 6-ethyl 3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate;MXEJHXZQYANNJK-SMEJFCCLSA-N
• CAS NO: 134575-38-5
• Molecular Formula: C₁₆H₁₉NO₄
• Molecular Weight: 289.32636
• Mol File: 134575-38-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1R,5S,6s)-3-benzyl 6-ethyl 3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,5S,6s)-3-benzyl 6-ethyl 3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate(134575-38-5)
• EPA Substance Registry System: (1R,5S,6s)-3-benzyl 6-ethyl 3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate(134575-38-5)

Safety Data

• Hazardous Substances Data: 134575-38-5(Hazardous Substances Data)

Usage

General Description

The chemical (1R,5S,6s)-3-benzyl 6-ethyl 3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate is a complex compound with a molecular structure containing a bicyclic ring system and multiple functional groups. It has a benzyl group, an ethyl group, and two carboxylate groups attached to the bicyclic ring. The compound is a derivative of azabicyclohexane and is likely to have pharmaceutical applications due to its structure and functional groups. Additionally, it may have potential use in medicinal chemistry as it contains structural features commonly found in drugs and bioactive molecules. The specific stereochemistry of the compound, denoted by the (1R,5S,6s) designation, indicates the configuration of the chiral centers in the molecule, which can influence its biological activity and pharmacological properties.

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 31970-04-4 1-carboxybenzyl-3-pyrrolidine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 681851-51-4 [(1α,5α,6β)-3-(4-benzyloxycarbonylamino-2,6-difluorophenyl)-3-azabicyclo[3.1.0]hex-6-yl]carbamic acid tert-butyl ester 
• 681851-50-3 [endo-(1R,5S)-3-(2,6-difluoro-4-nitro-phenyl)-3-aza-bicyclo[3.1.0]hex-6-yl]carbamic acid tert-butyl ester 
• 681851-52-5 [(1R,5S,6R)-3-(4-Amino-2,6-difluoro-phenyl)-3-aza-bicyclo[3.1.0]hex-6-yl]-carbamic acid tert-butyl ester 
• 134575-39-6 (1α,5α,6β)-6-tert-butoxycarbonylamino-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid benzyl ester 
• 134677-60-4 [1α,5α,6β]-6-(tert-Butoxycarbonylamino)-3-azabicyclo[3.1.0]hexane 
• 134677-59-1 [1α,5α,6β]-3-Benzyloxycarbonyl-3-azabicyclo[3.1.0] hexane-6-carboxylic acid 

Relevant articles and documents

Synthesis and diacylglycerol acyltransferase-1 inhibition of azabicyclo[3.1.0]hexane derivatives

We identified azabicyclo[3.1.0]hexane derivatives that are active diacylglycerol acyltransferase-1 (DGAT)-1 inhibitor. Among the azabicyclo[3.1.0]hexane series, compound 6b showed good in vitro activity toward human DGAT-1, selectivity toward DGAT-2, and

DEUTERATED HETEROCYCLIC COMPOUNDS AND THEIR USE AS IMAGING AGENTS

The present invention relates to deuterated and optionally detectably labeled compounds of formula (I): R1-A-R2 and formula (V) and salts thereof, wherein Rl, R2, A, and X10-X19 have any of

Conformational constraint in oxazolidinone antibacterials. Synthesis and structure-activity studies of (azabicyclo[3.1.0]hexylphenyl)oxazolidinones

The oxazolidinones are a new class of synthetic antibacterials effective against a broad range of pathogenic Gram-positive bacteria, including multi-drug-resistant strains. Linezolid is the first drug from this class to reach the market and has become an