134677-60-4

Basic information

• Product Name: Carbamic acid, (1alpha,5alpha,6beta)-3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester
• Synonyms: Carbamic acid, (1alpha,5alpha,6beta)-3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester;tert-Butyl (1R,5S,6r)-3-azabicyclo[3.1.0]hexan-6-ylcarbaMate;2-Methyl-2-propanyl (1R,5S,6r)-3-azabicyclo[3.1.0]hex-6-ylcarbama te;-3-azabicyclo[3.1.0]hexan-6-ylcarbamate;tert-Butyl (1R,5S,6r)
• CAS NO: 134677-60-4
• Molecular Formula: C₁₀H₁₈N₂O₂
• Molecular Weight: 198.26212
• Product Categories: N-BOC
• Mol File: 134677-60-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: Carbamic acid, (1alpha,5alpha,6beta)-3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (1alpha,5alpha,6beta)-3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester(134677-60-4)
• EPA Substance Registry System: Carbamic acid, (1alpha,5alpha,6beta)-3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester(134677-60-4)

Safety Data

• Hazardous Substances Data: 134677-60-4(Hazardous Substances Data)

Usage

General Description

Carbamic acid, (1alpha,5alpha,6beta)-3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester is a chemical compound known by its IUPAC name as 1,1-dimethylethyl (1R,5S,6R)-6-benzyloxymethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate. It is a bistrifluoroacetate salt with a molecular formula of C16H24N2O3?0.5(CF3CO2H) and a molecular weight of 350.37 g/mol. Carbamic acid, (1alpha,5alpha,6beta)-3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester is a derivative of carbamic acid and is commonly used as an intermediate in organic synthesis. It is also known for its potential applications in pharmaceutical research and development. However, it is important to handle this compound with care as it may pose hazards if mishandled or improperly used.

Upstream product

• 134575-38-5 3-benzyl 6-ethyl (1α,5α,6β)-3-azabicyclo[3.1.0]hexane-3,6-dicarboxylate 
• 134677-59-1 [1α,5α,6β]-3-Benzyloxycarbonyl-3-azabicyclo[3.1.0] hexane-6-carboxylic acid 
• 134575-39-6 (1α,5α,6β)-6-tert-butoxycarbonylamino-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid benzyl ester 

Downstream Products

• 681851-50-3 [endo-(1R,5S)-3-(2,6-difluoro-4-nitro-phenyl)-3-aza-bicyclo[3.1.0]hex-6-yl]carbamic acid tert-butyl ester 
• 681851-51-4 [(1α,5α,6β)-3-(4-benzyloxycarbonylamino-2,6-difluorophenyl)-3-azabicyclo[3.1.0]hex-6-yl]carbamic acid tert-butyl ester 
• 681851-52-5 [(1R,5S,6R)-3-(4-Amino-2,6-difluoro-phenyl)-3-aza-bicyclo[3.1.0]hex-6-yl]-carbamic acid tert-butyl ester 

Relevant articles and documents

6-(3-AZA-BICYCLO[3.1.0]HEX-3-YL)-2-PHENYL-PYRIMIDINES

The present invention relates to 6-(3-aza-bicyclo[3.1.0]hex-3-yl)-2-phenyl-pyrimidine derivatives and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.