1345822-98-1

Basic information

• Product Name: tert-butyl (3R)-3-[[(1R)-1-phenylethyl]amino]-4-(2,4,5-trifluorophenyl)butanoate maleate
• Synonyms: tert-butyl (3R)-3-[[(1R)-1-phenylethyl]amino]-4-(2,4,5-trifluorophenyl)butanoate maleate
• CAS NO: 1345822-98-1
• Molecular Weight: 509.523
• Mol File: 1345822-98-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (3R)-3-[[(1R)-1-phenylethyl]amino]-4-(2,4,5-trifluorophenyl)butanoate maleate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (3R)-3-[[(1R)-1-phenylethyl]amino]-4-(2,4,5-trifluorophenyl)butanoate maleate(1345822-98-1)
• EPA Substance Registry System: tert-butyl (3R)-3-[[(1R)-1-phenylethyl]amino]-4-(2,4,5-trifluorophenyl)butanoate maleate(1345822-98-1)

Safety Data

• Hazardous Substances Data: 1345822-98-1(Hazardous Substances Data)

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 1345822-93-6 tert-butyl 3-[[(1R)-1-phenylethyl]amino]-4-(2,4,5-trifluorophenyl)-but-2-enoate 
• 110-16-7 maleic acid 
• 764667-64-3 5-(1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 

Downstream Products

• 654671-78-0 sitagliptin phosphate 
• 1169707-30-5 (3R)-3-[[(1R)-1-phenylethyl]amino]-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one 
• 1345822-99-2 (3R)-3-[(1R)-1-phenylethylamino]-4-(2,4,5-trifluorophenyl)butanoic acid 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES

The present invention provides a process for preparing a compound of formula (I), or a pharmaceutically acceptable salt thereof, having the R-configuration, of formula (IA), or S-configuration of formula (IB), selectively over the other enantiomer.