1345824-06-7

Basic information

• Product Name: acetoxy((4-methyl)-N-tosylbenzenesulfonamidyl)iodosobenzene
• Synonyms: acetoxy((4-methyl)-N-tosylbenzenesulfonamidyl)iodosobenzene
• CAS NO: 1345824-06-7
• Molecular Weight: 587.456
• Mol File: 1345824-06-7.mol

Chemical Properties

• CAS DataBase Reference: acetoxy((4-methyl)-N-tosylbenzenesulfonamidyl)iodosobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: acetoxy((4-methyl)-N-tosylbenzenesulfonamidyl)iodosobenzene(1345824-06-7)
• EPA Substance Registry System: acetoxy((4-methyl)-N-tosylbenzenesulfonamidyl)iodosobenzene(1345824-06-7)

Safety Data

• Hazardous Substances Data: 1345824-06-7(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 3695-00-9 di(4-tosyl)amine 

Downstream Products

• 1374016-15-5 N-[2-(phenyl)prop-2-en-1-yl]-N,N-bis(p-toluenesulfonyl)imide 
• 1374016-43-9 N,N'-((2Z,4Z)-2,5-dimethylhexa-2,4-diene-1,6-diyl)bis(4-methyl-N-tosylbenzenesulfonamide) 
• 1374016-42-8 (Z)-N-(2,5-dimethylhexa-2,4-dien-1-yl)-4-methyl-N-tosylbenzenesulfonamide 
• 1414869-32-1 C₃₅H₄₂N₂O₈S₄ 
• 1414869-31-0 4-methyl-N-(2-oxo-2-phenylethyl)-N-tosylbenzenesulfonamide 

Relevant articles and documents

Synthesis of Diverse Aryliodine(III) Reagents by Anodic Oxidation?

An anodic oxidation enabled synthesis of hypervalent iodine(III) reagents from aryl iodides is demonstrated. Under mild electrochemical conditions, a range of aryliodine(III) reagents including iodosylarenes, (difunctionaliodo)arenes, benziodoxoles and diaryliodonium salts can be efficiently synthesized and derivatized in good to excellent yields with high selectivity. As only electrons serve as the oxidation reagents, this method offers a more straightforward and sustainable manner avoiding the use of expensive or hazardous chemical oxidants.

Defined hypervalent iodine(III) reagents incorporating transferable nitrogen groups: Nucleophilic amination through electrophilic activation

Only I and N: Hypervalent iodine(III) reagents with two reactive I-N single bonds have been isolated for the first time. Their solid-state and solution structures provide evidence for enhanced electrophilicity at iodine and nucleophilic character of the imine. As a result, improved reactivity in amination reactions and unprecedented nitrogen-transfer reactions under metal-free conditions are realized. Copyright

NOVEL IODINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF AS AMINATION AGENTS

The iodine compounds of the present invention corresponds to those of formula (I), wherein R1, R1' and X have several meanings. These iodine compounds gives rise to the amination of several substrates without the need of catalysts, especially metal catalysts, and confer to the amination reaction the further advantage of being performed under mild conditions, which is of interest for industrial-scale production of nitrogenated compounds with pharmaceutical, biological or medicinal applications. Therefore, the iodine compounds of the invention are useful as amination agents. The invention also discloses several processes for the preparation of the iodine compounds of formula (I).

Enantioselective metal-free diamination of styrenes

Metal-free and asymmetric: The first enantioselective diamination of styrenes simply requires a chiral hypervalent iodine(III) reagent as an oxidant and bismesylimide as a nitrogen source (see scheme, Ms=methanesulfonyl). The reaction proceeds under mild conditions and with high enantiomeric excess.