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Upstream product

• 100-39-0 benzyl bromide 
• 100-51-6 benzyl alcohol 
• 78287-52-2 4-aminobutanoic acid benzyl ester hydrochloride 
• 1356018-30-8 benzyl 4-formamidobutanoate 

Downstream Products

• 1356018-26-2 benzyl 4-(2-((S)-N-((S)-2,6-dioxo-1-phenethylpiperidin-3-yl)-2-methylbutanamido)acetamido)butanoate 
• 1356018-27-3 4-(2-((S)-N-((S)-2,6-dioxo-1-phenethylpiperidin-3-yl)-2-methylbutanamido)acetamido)butanoic acid 
• 1356018-29-5 (S)-N-((S)-2,6-dioxo-1-phenethylpiperidin-3-yl)-2-methyl-N-(2-oxo-2-(4-oxo-4-(pyren-1-ylmethylamino)butylamino)ethyl)butanamide 

Relevant academic research and scientific papers

ANTIFOULING AGENT FOR UNDERWATER ADHERING ORGANISMS HAVING AMINO ACID ISONITRILE SKELETON

PROBLEM TO BE SOLVED: To provide a novel antifouling agent for underwater adhering organisms having excellent characteristics compared with well-known antifouling agents. SOLUTION: An antifouling agent for underwater adhering organisms comprises a compound represented by formula (I) or salt thereof, or solvate thereof, as an active ingredient. COPYRIGHT: (C)2015,JPO&INPIT

MCR DENDRIMERS

The invention relates to a method for producing peptoidic, peptidic and chimeric peptidic-peptoidic dendrimers by multiple iterative multi-component reactions (MCR), in particular Ugi or Passerini multi-component reactions, to compounds produced in this way and to the use thereof.

Synthesis of (-)-julocrotine and a diversity oriented Ugi-approach to analogues and probes

An improved total synthesis of (-)-julocrotine in three steps from Cbz-glutamine, in 51% overall yield, is presented. To demonstrate the potential of the heterocyclic moiety for diversity oriented synthesis, a series of (-)-julocrotine analogues was synthesized by employing the heterocyclic precursor as an amino input in Ugi four-component reactions (Ugi-4CR) [1].