1345893-90-4

Basic information

• Product Name: tert-butyl 5-oxo-1-phenylhexylcarbamate
• Synonyms: tert-butyl 5-oxo-1-phenylhexylcarbamate
• CAS NO: 1345893-90-4
• Molecular Weight: 291.39
• Mol File: 1345893-90-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 5-oxo-1-phenylhexylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 5-oxo-1-phenylhexylcarbamate(1345893-90-4)
• EPA Substance Registry System: tert-butyl 5-oxo-1-phenylhexylcarbamate(1345893-90-4)

Safety Data

• Hazardous Substances Data: 1345893-90-4(Hazardous Substances Data)

Upstream product

• 75-36-5 acetyl chloride 
• 187974-79-4 (±)-tert-butyl (1-phenylbut-3-en-1-yl)carbamate 

Relevant articles and documents

Diastereoselective access to nonracemic 2-cis-substituted and 2,6-cis-disubstituted piperidines

Access to nonracemic amino ketones via a hydrozirconation/transmetalation/ acylation sequence applied to Boc-protected 1-aminobut-3-enes is presented. This method was applied to the stereoselective synthesis of cyclic imines (or iminiums) which were diastereoselectively converted into 2-cis-substituted and 2,6-cis-disubstituted piperidines. The potential of this approach in the field of alkaloid synthesis was illustrated by the synthesis of (-)-coniine and (-)-indolizidine 209D. Furthermore, access to indolizidines bearing a quaternary center could also be envisioned through this strategy.