13459-18-2

Basic information

• Product Name: 6-nitro-2-(2-hydroxyphenyl)benzoxazole
• Synonyms: 6-nitro-2-(2-hydroxyphenyl)benzoxazole
• CAS NO: 13459-18-2
• Molecular Weight: 256.218
• Mol File: 13459-18-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-nitro-2-(2-hydroxyphenyl)benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-nitro-2-(2-hydroxyphenyl)benzoxazole(13459-18-2)
• EPA Substance Registry System: 6-nitro-2-(2-hydroxyphenyl)benzoxazole(13459-18-2)

Safety Data

• Hazardous Substances Data: 13459-18-2(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 121-88-0 5-Nitro-2-aminophenol 
• 862095-14-5 2-phenyl-5'-nitrobenzo[d]benzo[h]-6-aza-1,3-dioxa-2-boracyclonon-6-ene 
• 74405-07-5 4-chloro-2,2-dimethyl-2H-benzo[e][1,3]oxazine 

Relevant articles and documents

Phenylboronic acid catalyzed-cyanide promoted, one-pot synthesis of 2-(2-hydroxyphenyl)benzoxazole derivatives

A novel, one-pot, phenylboronic acid catalyzed, cyanide promoted synthesis of 2-(2-hydroxyphenyl)benzoxazoles from salicylaldehydes and o-aminophenols is described. The synthesis is characterized by mild conditions, short reaction times, and simple workup of crystalline, high purity products.

STUDIES ON 1,3-BENZOXAZINES V. REACTION OF IMIDOYL CHLORIDES OF 1,3-BENZOXAZINES WITH 2-AMINOPHENOLS, o-PHENYLENEDIAMINES AND 2-AMINOTHIOPHENOL

A general synthetic method for benzoxazoles, benzimidazoles and benzthiazole is described.Treatment of the imidoyl chloride of 1,3-benzoxazine with 2-aminophenols gave the corresponding 2-hydroxyphenylbenzoxazoles in good yields.Similarly, 2-hydroxyphenylbenzimidazoles and 2-hydroxyphenylbenzthiazole were obtained using o-phenylenediamines and 2-aminothiophenol, respectively.