1345963-68-9Relevant academic research and scientific papers
Identification of novel plasmin inhibitors possessing nitrile moiety as warhead
Teno, Naoki,Gohda, Keigo,Wanaka, Keiko,Sueda, Takuya,Tsuda, Yuko
scheme or table, p. 6305 - 6309 (2011/12/02)
Lysine-nitrile derivatives having a trisubstituted benzene, which belongs to a new chemical class, were prepared and tested for inhibitory activities against plasmin and the highly homologous plasma kallikrein and urokinase. The use of the novel chemotype in the development of plasmin inhibitors has been demonstrated by derivatives of compound 9.
