1346151-47-0

Basic information

• Product Name: 6-methyl-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine
• Synonyms: 6-methyl-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine
• CAS NO: 1346151-47-0
• Molecular Weight: 286.354
• Mol File: 1346151-47-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-methyl-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine(1346151-47-0)
• EPA Substance Registry System: 6-methyl-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine(1346151-47-0)

Safety Data

• Hazardous Substances Data: 1346151-47-0(Hazardous Substances Data)

Upstream product

• 824-51-1 6-methyl-1H-pyrrolo<2,3-b>pyridine 
• 98-59-9 p-toluenesulfonyl chloride 
• 55052-27-2 6-chloro-7-azaindole 
• 143468-07-9 6-Chloro-1-methoxycarbonyl-1H-pyrrolo<2,3-b>pyridine 
• 55052-24-9 1H-Pyrrolo[2,3-b]pyridine-7-oxide 

Downstream Products

• 824-51-1 6-methyl-1H-pyrrolo<2,3-b>pyridine 
• 1255099-47-8 2,6-dimethyl-1H-pyrrolo[2,3-b]pyridine 

Relevant articles and documents

Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of sulphone-based CRTh2 antagonists

Monocyclic and bicyclic ring systems were investigated as the "core" section of a series of diphenylsulphone-containing acetic acid CRTh2 receptor antagonists. A range of potencies were observed and single-digit nanomolar potencies were obtained in both the monocyclic and bicyclic cores. Residence times for the monocyclic compounds were very short. Some of the bicyclic cores displayed better residence times. A methyl group in the northern part of the core, between the head and tail was a necessary requirement for the beginnings of long residence times. Variations of the tail substitution maximised potencies and residence times.