1346176-97-3Relevant academic research and scientific papers
Phase-transfer-catalyzed asymmetric synthesis of 1,1-disubstituted tetrahydroisoquinolines
Shirakawa, Seiji,Liu, Kun,Ito, Hironobu,Le, Thanh Nguyen,Maruoka, Keiji
supporting information; experimental part, p. 2614 - 2618 (2011/11/29)
A highly efficient catalytic asymmetric synthesis of 1,1-disubstituted tetrahydroisoquinolines has been achieved via asymmetric alkylation or Michael addition of 1-cyanotetrahydroisoquinolines using binaphthyl-modified N-spiro-type chiral phase-transfer c
