1346227-07-3

Upstream product

• 1346226-87-6 1,13-bis[4-(4H-chromen-4-on-2-yl)phenyl]-1,4,10,13-tetraoxa-7-azatridecane 
• 100-39-0 benzyl bromide 
• 4143-63-9 4'-hydroxyflavone 
• 1346226-72-9 1,13-bis[4-(4H-chromen-4-on-2-yl)phenyl]-7-(tert-butyloxycarbonyl)-1,4,10,13-tetraoxa-7-azatridecane 
• 1042743-76-9 C₂₇H₃₉NO₁₀S₂ 

Relevant academic research and scientific papers

Amine linked flavonoid dimers as modulators for P-glycoprotein-based multidrug resistance: Structure-activity relationship and mechanism of modulation

Here we report a great improvement in reversal potency of cancer drug resistance when flavonoid dimers possess a functionally substituted aminopolyethylene glycol linker. The most potent compound, 18, contains a N-benzyl group at the linker. It has many a

FLAVONOID DIMERS AND THEIR USE

This invention relates to bis-flavonoid compounds of formula Flavonoid-Linker-Y-Linker-Flavonoid, their synthesis and use for inhibiting multidrug resistance in chemotherapy and protozoan infection.