1346253-73-3Relevant academic research and scientific papers
Triphenylphosphine-catalyzed [3+2] cycloaddition of allenoate and active olefins: Syntheses of spirooxindole derivatives
Guo, Shanyan,Wang, Rendong,Li, Jian,Li, Chunju,Deng, Hongmei,Jia, Xueshun
, p. 2256 - 2258 (2011/11/05)
A series of spiro compounds was achieved by triphenylphosphine-catalyzed [3+2] cycloaddition between active methylenemalononitrile and ethyl 2,3-butadienoate. Careful investigation showed that the present method had high regioselectivity. The products have a spirooxindole skeleton, which is a motif common in many natural products and pharmaceutically active compounds. Georg Thieme Verlag Stuttgart - New York.
